Skip to main content

Screening Colonoscopy IDs Similar Rates of CRC for 45 to 49 as 50 to 54 Years

By Lori Solomon HealthDay Reporter

Medically reviewed by Carmen Pope, BPharm. Last updated on June 10, 2025.

via HealthDay

TUESDAY, June 10, 2025 -- Rates of colorectal cancer detection through colonoscopy screening are similar for adults aged 45 to 49 years and 50 to 54 years, according to a research letter published online June 2 in the Journal of the American Medical Association.

Jeffrey K. Lee, M.D., from Kaiser Permanente Northern California in Pleasanton, and colleagues investigated colorectal neoplasia yields at screening colonoscopy among adults aged 45 to 49 years (4,380 patients) versus 50 to 54 years (7,651 patients).

The researchers found that screening colonoscopy outcomes were generally slightly less frequent among the younger group versus the older group. However, only risk for any adenoma was statistically significant (35.4 versus 40.8 percent; adjusted risk ratio [aRR], 0.86; 95 percent confidence interval [CI], 0.82 to 0.90). Risk for advanced adenoma (3.8 versus 4.1 percent; aRR, 0.90; 95 percent CI, 0.75 to 1.09), advanced serrated lesion (1.5 versus 1.8 percent; aRR, 0.85; 95 percent CI, 0.63 to 1.14), any sessile serrated lesion (10.2 versus 10.4 percent; aRR, 0.98; 95 percent CI, 0.88 to 1.10), and colorectal cancer (0.1 versus 0.1 percent; aRR, 0.56; 95 percent CI, 0.15 to 2.07) did not differ significantly between the age groups.

"The current study findings extend the observation of similar screening colonoscopy detection rates for conventional adenomas and sessile serrated lesions in those aged 45 to 49 years versus 50 to 54 years and support the suggestion that there is likely no need to reduce adenoma or sessile serrated lesion detection rate benchmarks because of the infusion of younger patients into the screening pool," the authors write.

Abstract/Full Text (subscription or payment may be required)

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.

Read this next

Urinary Metal Levels Tied to Increased Risk for Later Heart Failure

THURSDAY, July 3, 2025 -- There are consistent associations between elevated urinary metal levels and increased heart failure risk over time across geographically diverse cohorts...

Higher Temperatures Tied to Increased Probability of Obstructive Sleep Apnea

THURSDAY, July 3, 2025 -- Higher temperatures across the globe are associated with an increased probability of having obstructive sleep apnea (OSA), according to a study published...

Tons of Turkey Bacon Products Recalled Due to Possible Listeria Contamination

THURSDAY, July 3, 2025 — Kraft Heinz Foods is recalling some 370,000 pounds of fully cooked turkey bacon products that may be contaminated with listeria, the U.S...

More news resources

Subscribe to our newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.