Risk for Postop Proliferative Vitreoretinopathy Lower With Cannabis Use
By Elana Gotkine HealthDay Reporter
.jpg?width=1200)
MONDAY, July 7, 2025 -- Patients undergoing retinal detachment (RD) repair with concomitant cannabis use have a lower risk for subsequent proliferative vitreoretinopathy (PVR) and requiring subsequent complex RD repair, according to a study published online July 3 in JAMA Ophthalmology.
Ahmed M. Alshaikhsalama, M.D., from the UT Southwestern Medical Center in Dallas, and colleagues examined the risk for developing PVR among patients with concomitant cannabis use who underwent RD repair in a retrospective cohort study. Participants underwent initial RD repair with pars plana vitrectomy with or without scleral buckle (SB), primary SB, or pneumatic retinopexy. Patients diagnosed with concomitant cannabis-related disorder together with confirmatory testing of cannabis in urine or blood were compared to a control group without documented use. After propensity score matching, each group had 1,193 patients.
The researchers found that compared with controls, patients with concomitant cannabis use with RD repaired by any method had a reduced risk for subsequent PVR (2.10 versus 4.36 percent; relative risk, 0.48) and requiring complex RD repair (3.10 versus 5.03 percent; relative risk, 0.62) at six months. For both outcomes, results were similar at one year.
"While cannabis use demonstrated a lower relative risk for PVR, the small absolute reduction (~2 percent) may not be clinically meaningful. Confounders may account for all the observed associations," the authors write.
Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted July 2025
Read this next
Capsular Tension Ring Implantation Linked to Improved Intraocular Lens Stability
MONDAY, June 23, 2025 -- Capsular tension ring (CTR) implantation is associated with improved stability of the intraocular lens (IOL), according to a review published online June...
Patients Who Fear Cataract Surgery Less Likely to Believe Surgery Will Improve Vision
TUESDAY, May 27, 2025 -- Neither health literacy nor understanding of cataract pathology is associated with fear of cataract surgery, according to a study published online March...
Aqueous Humor Liquid Biopsy Safe in Pediatric Retinoblastoma
WEDNESDAY, May 14, 2025 -- For pediatric patients with retinoblastoma, aqueous humor liquid biopsy via anterior chamber paracentesis is a safe and well-tolerated procedure...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.