Risk for Ovarian Cancer Increased for Women With Endometriosis
By Elana Gotkine HealthDay Reporter
THURSDAY, July 18, 2024 -- Women with endometriosis have an increased risk of ovarian cancer, with the highest risk seen for women with deep infiltrating endometriosis and/or ovarian endometriomas, according to a study published online July 17 in the Journal of the American Medical Association.
Mollie E. Barnard, Sc.D., from the University of Utah in Salt Lake City, and colleagues examined the associations of endometriosis subtypes with te incidence of ovarian cancer in a population-based cohort study using data from the Utah Population Database. A total of 78,893 women with endometriosis were matched in a 1:5 ratio to women without endometriosis.
The age at first endometriosis diagnosis was 36 years. Overall, 597 women had ovarian cancer. The researchers found that the risk for ovarian cancer was higher for women with versus those without endometriosis (adjusted hazard ratio, 4.20), and the risk for type I ovarian cancer was especially high (adjusted hazard ratio, 7.48). For all ovarian cancers, type I ovarian cancer, and type II ovarian cancer, the risk was highest for women with deep infiltrating endometriosis and/or ovarian endometriomas (adjusted hazard ratios, 0.66, 18.96, and 3.72, respectively).
"Studies that can better characterize the biology underlying these associations are urgently needed to guide improved ovarian cancer screening and prevention strategies among women with severe endometriosis, with or without other important ovarian cancer risk factors," the authors write.
One author received fees from Epi Excellence, and a second received fees from Epidemiologic Research & Methods.
Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted July 2024
Read this next
New Model Developed for Identifying DVT in Epithelial Ovarian Cancer
TUESDAY, June 17, 2025 -- A model with eight independent risk factors can predict the risk for deep vein thrombosis (DVT) in patients with epithelial ovarian cancer (EOC)...
Adverse Childhood Experiences Tied to Endometriosis Risk
FRIDAY, June 13, 2025 -- Early life adversity is associated with an increased risk of being diagnosed with endometriosis later in life, according to a study published online June...
American College of Obstetricians and Gynecologists, May 16-18
The annual meeting of the American College of Obstetricians and Gynecologists (ACOG) was held from May 16 to 18 in Minneapolis and was attended by more than 4,000...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.