Risk for Developing Type 1 Diabetes Doubled With Paternal Link
By Lori Solomon HealthDay Reporter
FRIDAY, Aug. 16, 2024 -- Individuals are less likely to have type 1 diabetes if their mother has the condition than if their father is affected, according to a study scheduled to be presented at the annual meeting of the European Association for the Study of Diabetes, being held from Sept. 9 to 13 in Madrid.
Lowri A. Allen, M.B.Ch.B., from Cardiff University in the United Kingdom, and colleagues conducted a meta-analysis across five cohorts of individuals with type 1 diabetes (total, 11,475 individuals) to compare the proportion of individuals with affected fathers versus mothers.
The researchers found that almost twice as many individuals had an affected father versus mother (overall odds ratio [OR], 1.79). The proportion of individuals with an affected father was higher both among individuals diagnosed with type 1 diabetes older than 18 years (OR, 1.64) and those 18 years or younger (OR, 1.80). There was an excess of individuals with affected fathers only if parental diagnosis was before offspring birth compared with diagnosis after birth. Age at diagnosis and type 1 diabetes-free survival curves were similar among offspring of affected fathers and mothers.
"Further research is needed but ultimately, we hope that it might be possible in the future to offer treatments at the very earliest stages of life to prevent the onset of type 1 diabetes in individuals who are at particularly high risk of the disease," Allen said in a statement.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted August 2024
Read this next
Pulmonary Embolism More Common in Children Than Previously Thought
THURSDAY, May 22, 2025 -- Pulmonary embolism (PE) is more common in children than previously thought, according to a study presented at the American Thoracic Society 2025...
Persistent, New Mucus Plugs Associated With Faster Decline in FEV1 in COPD
WEDNESDAY, May 21, 2025 -- For patients with chronic obstructive pulmonary disease (COPD), persistent and newly formed mucus plugs are associated with a faster decrease in forced...
Combinations of Chronic, Physical Illnesses Up the Risk of Subsequent Depression
WEDNESDAY, May 21, 2025 -- Certain groups of physical multimorbidity may be associated with a higher risk of subsequent depression, according to a study published online May 13...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.