Racial, Ethnic Disparities Seen in Mortality With Early-Onset Colorectal Cancer
By Lori Solomon HealthDay Reporter
.jpeg?width=1200)
TUESDAY, Nov. 26, 2024 -- Racial and ethnic disparities exist in early-onset colorectal cancer (EOCRC) mortality, especially in those aged younger than 50 years, according to a study published online Nov. 22 in JAMA Network Open.
Joshua Demb, Ph.D., from the University of California, San Diego, in La Jolla, and colleagues investigated racial and ethnic differences in EOCRC mortality. The analysis included California Cancer Registry data for 22,834 individuals (aged 18 to 49 years) with EOCRC (2000 through 2019), with a median follow-up of 4.2 years.
The researchers found that compared with non-Hispanic White individuals, higher EOCRC mortality was seen for Native Hawaiian or Other Pacific Islander (adjusted hazard ratio [aHR], 1.34) and non-Hispanic Black (aHR, 1.18) individuals. When disaggregating Asian American ethnic groups, there was notable heterogeneity, but no single group had increased EOCRC mortality risk in a fully adjusted analysis. In the base model (adjusting for age, sex, and tumor characteristics), Hispanic individuals had higher EOCRC mortality (aHR, 1.15), but the association disappeared when further adjusting for neighborhood socioeconomic status. Similarly, in the base model, there was higher EOCRC mortality among Southeast Asian individuals (aHR, 1.17), which disappeared with the addition of insurance status to the model.
"These results provide evidence of the role of social determinants of health in explaining these differences," the authors write.
One author disclosed ties to the diagnostics industry.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted November 2024
Read this next
Dietary Patterns Influence Development of Overactive Bladder
FRIDAY, June 20, 2025 -- Dietary patterns influence the development of overactive bladder (OAB), according to a study published online May 12 in Frontiers of Nutrition. Yiming...
Mismatch Repair Germline Pathogenic Variants Could Predispose to Uveal Melanoma
FRIDAY, June 20, 2025 -- Mismatch repair (MMR) germline alterations are enriched among patients with uveal melanoma (UM), according to a study published online June 18 in JAMA...
Tinnitus Linked to Impaired Cognitive Function
FRIDAY, June 20, 2025 -- Individuals with versus those without tinnitus have significantly lower scores on cognitive function tests, according to a study published online May 29...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.