Racial, Ethnic Disparities Seen in Mortality With Early-Onset Colorectal Cancer
By Lori Solomon HealthDay Reporter
.jpeg?width=1200)
TUESDAY, Nov. 26, 2024 -- Racial and ethnic disparities exist in early-onset colorectal cancer (EOCRC) mortality, especially in those aged younger than 50 years, according to a study published online Nov. 22 in JAMA Network Open.
Joshua Demb, Ph.D., from the University of California, San Diego, in La Jolla, and colleagues investigated racial and ethnic differences in EOCRC mortality. The analysis included California Cancer Registry data for 22,834 individuals (aged 18 to 49 years) with EOCRC (2000 through 2019), with a median follow-up of 4.2 years.
The researchers found that compared with non-Hispanic White individuals, higher EOCRC mortality was seen for Native Hawaiian or Other Pacific Islander (adjusted hazard ratio [aHR], 1.34) and non-Hispanic Black (aHR, 1.18) individuals. When disaggregating Asian American ethnic groups, there was notable heterogeneity, but no single group had increased EOCRC mortality risk in a fully adjusted analysis. In the base model (adjusting for age, sex, and tumor characteristics), Hispanic individuals had higher EOCRC mortality (aHR, 1.15), but the association disappeared when further adjusting for neighborhood socioeconomic status. Similarly, in the base model, there was higher EOCRC mortality among Southeast Asian individuals (aHR, 1.17), which disappeared with the addition of insurance status to the model.
"These results provide evidence of the role of social determinants of health in explaining these differences," the authors write.
One author disclosed ties to the diagnostics industry.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted November 2024
Read this next
Myocardial Fibrosis Linked to Ventricular Arrhythmia in Male Endurance Athletes
TUESDAY, July 22, 2025 -- Myocardial fibrosis is independently associated with the onset of ventricular arrhythmia in male veteran endurance athletes, according to a study...
Digital Model Based on Noninvasive Factors Shows Accuracy for Identifying IBD in Children
TUESDAY, July 22, 2025 -- A model based on noninvasive tests shows high accuracy as a digital tool for the rapid identification of children with inflammatory bowel disease (IBD)...
Prevalence of Extremely Severe Obesity Increasing in Children
TUESDAY, July 22, 2025 -- From 2008 to 2023, there was an increase in the prevalence of extremely severe obesity in children, especially among older adolescents and non-Hispanic...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.