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Proinflammatory Diet Tied to Higher Risk for Chronic Kidney Disease

By Lori Solomon HealthDay Reporter

Medically reviewed by Carmen Pope, BPharm. Last updated on April 23, 2025.

via HealthDay

WEDNESDAY, April 23, 2025 -- Individuals who eat a proinflammatory diet have a higher likelihood of chronic kidney disease, according to a review published online April 16 in the Journal of Health, Population and Nutrition.

Amirhossein Ataei Kachouei, from Isfahan University of Medical Sciences in Iran, and colleagues conducted a systematic literature review to examine the association between the dietary inflammatory index and chronic kidney disease and estimated glomerular filtration rate. The random-effects model was used for statistical analysis, and pooled effect sizes were reported as odds ratios.

Based on 13 cross-sectional studies, the researchers found that higher dietary inflammatory index scores were associated with significantly higher odds of chronic kidney disease (odds ratio, 1.36) and a low estimated glomerular filtration rate (odds ratio, 1.58).

"This study found a significant positive association between the dietary inflammatory index and the odds of chronic kidney disease and low-estimated glomerular filtration rate, suggesting a higher likelihood of chronic kidney disease in individuals who adhere to a proinflammatory diet," the authors write. "Large-scale prospective cohort studies are required to confirm these findings, particularly by assessing different indicators of kidney function."

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Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

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