Where One Lives Impacts Dementia Risk
By Lori Solomon HealthDay Reporter
.jpg?width=1200)
FRIDAY, Dec. 13, 2024 -- Neighborhood disadvantage is more strongly associated with measures of cardiometabolic health and cognition in individuals without mild cognitive impairment (MCI) compared to those with MCI, according to a study published online Dec. 6 in Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring.
Sudarshan Krishnamurthy, from the Wake Forest University School of Medicine in Winston-Salem, North Carolina, and colleagues investigated the relationship between neighborhood disadvantage with measures of cardiometabolic health and cognition. Analysis included 537 adults (aged >55 years) participating in the Wake Forest Alzheimer's Disease Research Center Healthy Brain Study (between 2016 and 2021); 39.3 percent had MCI.
The researchers found that Area Deprivation Index (ADI) was positively associated with blood pressure and cardiometabolic index (CMI). There was a negative association between ADI and global and Preclinical Alzheimer's Cognitive Composite scores in cognitively unimpaired individuals. In individuals with MCI, ADI was only positively associated with hemoglobin A1c.
"Neighborhood disadvantage is associated more strongly with measures of cardiometabolic health and cognition among cognitively unimpaired individuals rather than MCI," the authors write. "These findings demonstrate a need for structural solutions to address social determinants of health in an attempt to reduce cardiometabolic and cognitive risks."
One author disclosed ties to the biopharmaceutical industry.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted December 2024
Read this next
Brain Age Gap May Mediate Influence of Cognitive Impairment Risk Factors
TUESDAY, June 24, 2025 -- The brain age gap (BAG) plays a role in mediating the influence of cognitive impairment risk factors on cognitive function, especially among individuals...
Dementia Caregivers Have Modifiable Risk Factors Increasing Their Own Risk
FRIDAY, June 20, 2025 -- Six in 10 dementia caregivers report having at least one modifiable risk factor that could increase their own chances of developing dementia, according to...
Tinnitus Linked to Impaired Cognitive Function
FRIDAY, June 20, 2025 -- Individuals with versus those without tinnitus have significantly lower scores on cognitive function tests, according to a study published online May 29...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.