OD Deaths Decline in U.S., Driven By Drop In Opioid Fatalities
FRIDAY, Feb. 21, 2025 -- America’s opioid crisis is showing signs of subsiding, a new report from the U.S. Centers for Disease Control and Prevention (CDC) says.
Drug overdose deaths (OD) decreased by 4% between 2022 and 2023, according to the CDC’s National Center for Health Statistics.
The overall OD death rate fell from 32.6 deaths per 100,000 people in 2022 to 31.3 deaths per 100,000 in 2023, the CDC says.
This reduction was driven by a decline in OD deaths related to opioids, the report says.
“Nationally, between 2022 and 2023, the age-adjusted rate of drug overdose deaths decreased for deaths involving any opioid and synthetic opioids other than methadone (which includes fentanyl),” concluded the team led by senior researcher Arialdi Minino, a CDC statistician.
However, OD deaths increased among users of stimulant drugs like methamphetamine and cocaine, researchers noted.
Across the country, drug OD deaths decreased in 20 states and did not change significantly in 25 states, researchers found.
The death rate increased in six states: Alabama, Alaska, California, Nevada, Oregon and Washington.
Changes in OD death rates varied between states based on specific drug types, the report says:
-
Drug overdose deaths involving any opioid decreased in 20 states and increased in nine states.
-
Deaths involving synthetic opioids other than methadone decreased in 17 states and increased in 11.
-
OD deaths involving psychostimulants with abuse potential other than methadone decreased in nine states and increased in six.
-
Rates for deaths involving cocaine decreased in three states and increased in 13.
West Virginia (81.9 deaths per 100,000), the District of Columbia (60.7), Delaware (53), Tennessee (52.3), and Louisiana (50.6) had the highest OD death rates in the U.S. in 2023, researchers said.
The states with the lowest rates were Nebraska (9 deaths per 100,000), South Dakota (11.2), Iowa (14.9), North Dakota (16.4), Montana (17.1), Arkansas (17.7), and Texas (18.5).
Sources
- U.S. Centers for Disease Control and Prevention, report, Feb. 20, 2025
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.
Read this next
Cancer Patients Getting Needed Painkillers Despite Opioid Crisis Response
WEDNESDAY, Sept. 24, 2025 — The fight against America’s opioid crisis does not appear to have cost cancer patients the painkillers they need, a new study says. There...
Over-The-Counter Sales Of OD-Reversal Drug, Narcan Nasal Spray, Have Been A Bust
TUESDAY, Sept. 16, 2025 — Over-the-counter sales have tanked for the overdose reversal drug naloxone, likely due to its high price, a new study says. Naloxone (Narcan) is a...
Inmates Less Likely To OD After Release If Provided Opioid Addiction Meds In Jail
FRIDAY, Sept. 12, 2025 — County jail inmates who receive medication to treat their opioid addiction have a lower risk of overdose after their release, a new study...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.