Skip to main content

Moderate-to-Severe Psoriasis Tied to Lower Fertility Rates in Women

Medically reviewed by Drugs.com.

By Lori Solomon HealthDay Reporter

WEDNESDAY, June 21, 2023 -- Patients with moderate-to-severe psoriasis have lower fertility rates than women without psoriasis, according to a study published online June 7 in JAMA Dermatology.

Teng-Chou Chen, Ph.D., from the School of Health Sciences at the University of Manchester in the United Kingdom, and colleagues used data from 63,681 patients with psoriasis and 318,405 matched controls to assess differences in fertility rates and obstetric outcomes.

The researchers found lower fertility rates (rate ratio, 0.75) among patients with moderate-to-severe psoriasis. Pregnancies in patients with psoriasis had a higher risk for loss (odds ratio, 1.06) compared with pregnancies in matched controls without psoriasis. The two groups were similar with respect to the risks for antenatal hemorrhage, preeclampsia, and gestational diabetes.

"In this cohort study, patients with moderate-to-severe psoriasis had a lower fertility rate, and the risk of pregnancy loss was higher than in matched comparators without psoriasis," the authors write. "Future research should identify the mechanism of increased risk of pregnancy loss among patients with psoriasis."

Several authors disclosed financial ties to the pharmaceutical industry.

Abstract/Full Text

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2024 HealthDay. All rights reserved.

Posted June 2023

Read this next

ASCO: Survivors of Early Breast Cancer Can Successfully Attempt Pregnancy

THURSDAY, May 23, 2024 -- Most survivors of stage 0 to III breast cancer who attempt pregnancy postdiagnosis are able to become pregnant and have a live birth, according to a...

Infertility Treatment Linked to Heart Disease Hospitalization

TUESDAY, May 21, 2024 -- Infertility treatment is associated with an increased risk for hospitalization due to heart disease, according to a study published in the May issue of...

Coexistence of Psoriatic Arthritis, Atopic Dermatitis May Offer Treatment Insights

MONDAY, May 13, 2024 -- Psoriatic arthritis (PsA) and atopic dermatitis (AD) can coexist, and the presence of both conditions may mean special attention should be given to...

More news resources

Subscribe to our newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.