Metabolic Syndrome Score Trajectories Associated With Risk for Cancer
By Elana Gotkine HealthDay Reporter
MONDAY, March 11, 2024 -- Metabolic syndrome (MetS) score trajectories are associated with a subsequent risk for cancer, according to a study published online March 11 in Cancer.
Li Deng, Ph.D., from Beijing Shijitan Hospital, and colleagues examined the relationship between MetS score trajectory patterns and new-onset cancer in a large prospective cohort study involving 44,115 participants.
The researchers identified four MetS score trajectory patterns: low-stable, moderate-low, moderate-high, and elevated-increasing (4,657, 18,018, 18,288, and 3,152 individuals, respectively). The elevated-increasing trajectory pattern was associated with an increased risk for overall, breast, endometrial, kidney, colorectal, and liver cancers compared with a low-stable trajectory pattern (hazard ratios, 1.27, 2.11, 3.33, 4.52, 2.54, and 1.61, respectively). The elevated-increasing trajectory pattern was significantly associated with subsequent breast, endometrial, colorectal, and liver cancers among those with chronic inflammation (C-reactive protein levels ≥3 mg/L).
"This research suggests that proactive and continuous management of metabolic syndrome may serve as an essential strategy in preventing cancer," senior author Han-Ping Shi, M.D., Ph.D., of Capital Medical University in Beijing, said in a statement. "Our study can guide future research into the biological mechanisms linking metabolic syndrome to cancer, potentially resulting in targeted treatments or preventive strategies. Formal evaluation of these interventions will be needed to determine if they are able to modulate cancer risk."
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted March 2024
Read this next
Survival Gains Seen With Assignment to Experimental Group in Cancer Trials
TUESDAY, April 30, 2024 -- For patients with solid tumors, assignment to an experimental group in trials of investigational drugs yields significant survival gains, according to a...
Variation ID'd in Risk for Second Primary Cancer After Breast Cancer
TUESDAY, April 30, 2024 -- The risk for second primary cancer (SPC) after breast cancer (BC) varies with gender, age, and socioeconomic status, according to a study published...
People With Opioid Use Disorder Less Likely to Receive Palliative Care
MONDAY, April 29, 2024 -- People with opioid use disorder (OUD) are less likely to receive palliative care during the last 90 days before death, according to a study published...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.