Machine Learning Model Can Diagnose Meniere Disease
By Elana Gotkine HealthDay Reporter
FRIDAY, Oct. 4, 2024 -- A machine learning model based on pure-tone audiometry features can diagnose Meniere disease (MD) and predict endolymphatic hydrops (EH), according to a study published online Aug. 28 in Otolaryngology-Head and Neck Surgery.
Xu Liu, M.D., from Fudan University in Shanghai, and colleagues collected gadolinium-enhanced magnetic resonance imaging sequences and pure-tone audiometry data in a retrospective study. Based on the air conduction thresholds of pure-tone audiometry, basic and multiple analytical features were engineered. The engineered features were used to train five classical machine learning models to diagnose MD. The models with excellent performance were selected to predict EH.
The researchers found that the winning light gradient boosting (LGB) machine learning model demonstrated remarkable performance for diagnosis of MD, achieving accuracy of 87 percent, sensitivity and specificity of 83 and 90 percent, and an area under the receiver operating characteristic curve of 0.95, comparing favorably with experienced clinicians. The LGB model had 78 percent accuracy for EH prediction and outperformed the other three models. Specific pure-tone audiometry features that are essential for both MD diagnosis and EH prediction include standard deviation and mean of the whole-frequency hearing, audiogram peak, and hearing at low frequencies (notably at 250 Hz).
"The study showed promising diagnostic capabilities, indicating the potential of machine learning based on pureātone audiometry results as an MD screening method," the authors write.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.
Posted October 2024
Read this next
Helping Others Linked to Higher Level of Cognitive Function
THURSDAY, Aug. 21, 2025 -- Helping others, both via formal volunteering and informal helping, is associated with higher levels of cognitive function and slower cognitive decline...
TAR-200 Monotherapy Promising for BCG-Unresponsive Bladder Cancer
THURSDAY, Aug. 21, 2025 -- For patients with Bacillus Calmette-Guérin (BCG)-unresponsive high-risk non-muscle-invasive bladder cancer (NMIBC), an intravesical...
Work-Related Income Drops for Parents of Children Diagnosed With Type 1 Diabetes
THURSDAY, Aug. 21, 2025 -- Work-related income decreases sharply for mothers and fathers of children diagnosed with type 1 diabetes, with similar effects across sociodemographic...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.