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Light-to-Moderate Wine Consumption Tied to Lower Cardiovascular Disease Risk

By Lori Solomon HealthDay Reporter

Medically reviewed by Carmen Pope, BPharm. Last updated on Dec 19, 2024.

via HealthDay

THURSDAY, Dec. 19, 2024 -- Light-to-moderate consumption of wine, measured through an objective urinary biomarker, is associated with lower cardiovascular disease (CVD) risk in an older Mediterranean population, according to a study published online Dec. 18 in the European Heart Journal.

Inés Domínguez-López, from the University of Barcelona in Spain, and colleagues evaluated the association between urinary tartaric acid, an objective biomarker of wine consumption, and the rate of a composite clinical CVD event. The analysis included 1,232 participants (685 incident cases of CVD and a random subcohort of 625 participants, including 78 overlapping cases).

The researchers found that tartaric acid was correlated with self-reported wine consumption at baseline (r = 0.46). To better assess risk patterns, five categories of post hoc urinary tartaric acid excretion were analyzed. Concentrations of 3 to 12 and 12 to 35 μg/mL (about three to 12 and 12 to 35 glasses/month of wine) were associated with lower CVD risk (hazard ratios [95 percent confidence intervals], 0.62 [0.38 to 1.00; P = 0.050] and 0.50 [0.27 to 0.95; P = 0.035], respectively). Associations were less significant when analyzing self-reported wine consumption and CVD risk.

"This study examines the importance of moderate wine consumption within a healthy dietary pattern, such as the Mediterranean diet," lead author Ramon Estruch, M.D., Ph.D., also from the University of Barcelona, said in a statement. "Until now, we believed that 20 percent of the effects of the Mediterranean diet could be attributed to moderate wine consumption; however, in light of these results, the effect may be even greater."

Several authors disclosed ties to the pharmaceutical and culinary industries.

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Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

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