Increased Risk for CVD Seen for Women With Premenstrual Disorders
By Elana Gotkine HealthDay Reporter
THURSDAY, July 17, 2025 -- Women with premenstrual disorders (PMDs) have an increased risk for cardiovascular diseases (CVDs), according to a study published online July 11 in Nature Cardiovascular Research.
Yihui Yang, M.P.H., from Karolinska Institutet in Stockholm, and colleagues used a Swedish nationwide population-based matched cohort study from 2001 to 2022 and a sibling matched cohort to examine whether women with PMDs have an increased risk for CVD. The population analysis included 99,411 women with PMDs, and the sibling analysis included 36,061 women with PMDs.
The researchers found that women with PMDs had a higher risk for any CVD compared with those without PMDs in the population analysis and the sibling analysis (adjusted hazard ratios, 1.11 and 1.10, respectively). For PMDs diagnosed before age 25 years and PMDs with comorbid perinatal depression, the risk was particularly pronounced.
"The increased risk was particularly clear in women who were diagnosed before the age of 25 and in those who had also experienced postnatal depression, a condition that can also be caused by hormonal fluctuations," Yang said in a statement.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted July 2025
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