Incidence of Cardiovascular Disease Higher for Seniors With Cancer
By Elana Gotkine HealthDay Reporter
MONDAY, Sept. 23, 2024 -- The incidence of a composite cardiovascular disease (CVD) end point is increased among older adults with cancer, especially those with metastatic, hematological, and lung cancer, according to a study published online Sept. 23 in Cancer.
Jaidyn Muhandiramge, M.D., from Monash University in Melbourne, Australia, and colleagues conducted a secondary analysis of the Aspirin in Reducing Events in the Elderly (ASPREE) trial to examine the impact of cancer and cancer treatment on a composite CVD end point. Overall, 1,392 of the 15,454 Australian and U.S. ASPREE participants had a cancer diagnosis.
The researchers observed greater rates of CVD in the cancer risk-set versus the cancer-free risk-set (20.8 versus 10.3 events per 1,000 person-years; incidence rate ratio, 2.03); increased incidence was seen for myocardial infarction, hospitalization for heart failure, overall stroke, and ischemic stroke. After adjustment for clinically significant risk factors for CVD, the increased incidence persisted. The greatest incidence was seen for metastatic, hematological, and lung cancer. An increased risk for CVD was seen in association with chemotherapy. Across aspirin and placebo groups, the rates of CVD were similar.
"The clinical implications of our findings lie in the impact of CVD on mortality and the fact that with appropriate screening and management, cardiovascular risk in cancer survivors can be mitigated," the authors write.
Several authors disclosed ties to the pharmaceutical industry.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted September 2024
Read this next
Race Definitions Have Limited Impact on Cancer Rates in Whites, Blacks, Asians
MONDAY, July 21, 2025 -- Race definitions have limited impact on cancer rates for Whites, Blacks, and Asians, but do impact rates in multiracial individuals, according to a study...
Updated Guidance Improves Staging of HPV-Positive Oropharyngeal Cancer
MONDAY, July 21, 2025 -- Version nine of the American Joint Committee on Cancer (AJCC) and Union for International Cancer Control staging system (AJCC9V) human papillomavirus...
Increased Risk for CVD Seen for Women With Premenstrual Disorders
THURSDAY, July 17, 2025 -- Women with premenstrual disorders (PMDs) have an increased risk for cardiovascular diseases (CVDs), according to a study published online July 11 in...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.