Hormone Therapy Not Associated With Glioma Risk in Women
By Elana Gotkine HealthDay Reporter
WEDNESDAY, Jan. 15, 2025 -- There seems to be no association between hormone therapy (HT) and glioma risk among U.S. women, according to a study published online Jan. 14 in Menopause.
Jinyu Pan, from the Chongqing General Hospital and Chongqing University in China, and colleagues analyzed data from 75,335 women aged 50 to 78 years in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial who were followed for a median of 11.82 years to examine the association between HT use and glioma risk.
The researchers found that 101 women were diagnosed with glioma during the follow-up period. There was no significant association between HT use and glioma risk after adjusting for relevant variables (hazard ratio, 1.6; 95 percent confidence interval, 0.75 to 1.81). When considering HT status or duration of use, no significant associations were found. In a subgroup analysis, a significant positive association was only seen in the group with at least a college degree (hazard ratio, 3.00; 95 percent confidence interval, 1.02 to 8.84). For education, the interaction effect was not significant.
"This study found that, although there is a known sex difference in the incidence of gliomas, with women being six times more likely to develop the disease compared with men, there does not appear to be an association between glioma and hormone therapy use in postmenopausal women," Stephanie Faubion, M.D., medical director of The Menopause Society, said in a statement. "However, larger prospective studies with longer duration of follow-up are needed to confirm these results."
Abstract/Full Text (subscription or payment may be required)
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted January 2025
Read this next
ENDO: Superior Weight Loss Seen With Tirzepatide and Menopausal Hormone Therapy Use
TUESDAY, July 15, 2025 -- In postmenopausal women with overweight or obesity receiving tirzepatide, use of menopausal hormone therapy (MHT) is associated with superior weight loss...
Many Indicators of Anger Expression Decrease With Age in Women
THURSDAY, July 10, 2025 -- Aging is significantly related to anger in women, with most indicators of anger expression decreasing with age, according to a study published online...
Stratifying BMI by Waist Circumference Improves Mortality Risk Prediction in Postmenopausal Women
THURSDAY, July 10, 2025 -- Stratifying body mass index (BMI) categories by waist circumference (WC) thresholds improves mortality risk prediction in postmenopausal women...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.