Hormone Therapy Not Associated With Glioma Risk in Women
By Elana Gotkine HealthDay Reporter
WEDNESDAY, Jan. 15, 2025 -- There seems to be no association between hormone therapy (HT) and glioma risk among U.S. women, according to a study published online Jan. 14 in Menopause.
Jinyu Pan, from the Chongqing General Hospital and Chongqing University in China, and colleagues analyzed data from 75,335 women aged 50 to 78 years in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial who were followed for a median of 11.82 years to examine the association between HT use and glioma risk.
The researchers found that 101 women were diagnosed with glioma during the follow-up period. There was no significant association between HT use and glioma risk after adjusting for relevant variables (hazard ratio, 1.6; 95 percent confidence interval, 0.75 to 1.81). When considering HT status or duration of use, no significant associations were found. In a subgroup analysis, a significant positive association was only seen in the group with at least a college degree (hazard ratio, 3.00; 95 percent confidence interval, 1.02 to 8.84). For education, the interaction effect was not significant.
"This study found that, although there is a known sex difference in the incidence of gliomas, with women being six times more likely to develop the disease compared with men, there does not appear to be an association between glioma and hormone therapy use in postmenopausal women," Stephanie Faubion, M.D., medical director of The Menopause Society, said in a statement. "However, larger prospective studies with longer duration of follow-up are needed to confirm these results."
Abstract/Full Text (subscription or payment may be required)
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted January 2025
Read this next
Rate of Sexual Dysfunction Similar in Middle-Aged, Older Women
MONDAY, Aug. 18, 2025 -- Older women experience female sexual dysfunction (FSD) at similar rates as midlife women but report less sexual distress, according to a study published...
Increasing Sit-to-Stand Transitions Lowers BP in Postmenopausal Women
FRIDAY, Aug. 8, 2025 -- Changing sedentary behaviors is feasible for postmenopausal women with overweight and obesity, and increasing sit-to-stand transitions (STSTs) is...
Study Offers Comprehensive Evaluation of Survival Parameters for Pediatric CNS Tumors
MONDAY, Aug. 4, 2025 -- The survival probabilities of pediatric central nervous system (CNS) tumors in Europe have been explored in a study published in the August issue of The...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.