Higher Education Level Tied to Decline in Executive Function After Stroke
By Elana Gotkine HealthDay Reporter
THURSDAY, April 3, 2025 -- Stroke survivors with a higher education level have a steeper decline in executive function, according to a study published online March 26 in JAMA Network Open.
Mellanie V. Springer, M.D., from the University of Michigan in Ann Arbor, and colleagues examined the association of education level with poststroke cognitive decline in an individual participant data meta-analysis of four U.S. cohort studies. The analysis included 2,019 initially dementia-free stroke survivors: 16.7, 30.4, 24.0, and 28.9 percent had less than a high school education, had completed high school, had some college, and had a college degree or higher, respectively. Median follow-up time after stroke was 4.1 years.
The researchers found that college graduates had higher initial poststroke performance in global cognition, executive function, and memory compared with those with less than a high school degree (1.09, 1.81, and 0.99 points higher, respectively). The decline in executive function was faster among college graduates and those with some college education compared with stroke survivors with less than a high school education (–0.44 and –0.30 points/year faster, respectively). There was no association for education level with declines in global cognition or memory. The association of education with cognitive decline was not modified by age.
"Higher education level may be associated with faster cognitive decline after stroke. In designing interventions to slow cognitive decline after stroke, researchers should consider evaluating whether the efficacy of such interventions [varies] by education level," the authors write.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.
Posted April 2025
Read this next
Declining Childhood Vaccination May Increase Risk for Vaccine-Preventable Infections
WEDNESDAY, April 30, 2025 -- Declining childhood vaccination rates may increase outbreaks of eliminated vaccine-preventable infections within the United States, leading to a...
AACR: Incidence-Based Mortality Dropping for Young Women With Breast Cancer
TUESDAY, April 29, 2025 -- Incidence-based mortality (IBM) declined from 2010 to 2020 among women aged 20 to 49 years diagnosed with breast cancer, according to a study presented...
AACR: Nonsurgical Treatment Feasible for Mismatch Repair-Deficient Tumors
TUESDAY, April 29, 2025 -- A neoadjuvant programmed cell death 1 (PD-1) blockade enables nonoperative management among patients with early-stage mismatch repair-deficient (dMMR)...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.