Fasting at Night May Aid Glucose Metabolism in Night-Shift Workers
By Lori Solomon HealthDay Reporter
THURSDAY, Nov. 14, 2024 -- Fasting at night prevents impairments in glucose tolerance among simulated night-shift work, according to a study published online Oct. 18 in Diabetologia.
Stephanie Centofanti, Ph.D., from University of South Australia in Adelaide, and colleagues assigned healthy, non-shift-working adults without obesity to fasting-at-night (20 individuals), snack-at-night (17 individuals), or meal-at-night (18 individuals) conditions.
The researchers found that night-shift work significantly impaired insulin sensitivity, as measured by insulin area under the curve (AUC) and the insulin sensitivity index across all conditions. Measures of insulinogenic index were significantly heightened in the fasting-at-night condition only, resulting in a day-by-condition interaction in glucose AUC, with glucose tolerance impaired in the meal-at-night and snack-at-night conditions compared with the fasting-at-night condition. There was also a day-by-condition interaction for nonesterified fatty acid AUC, which was higher in the meal-at-night and snack-at-night conditions compared with the fasting-at-night condition.
"The timing of food intake has a critical effect on glucose metabolism during simulated night-shift work, which was readily amendable to a meal retiming intervention," the authors write. "Meal timing advice should be considered for existing dietary guidelines, industry recommendations, and workplace policy to improve health and reduce the burden of metabolic disease on night-shift workers."
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted November 2024
Read this next
Myocardial Fibrosis Linked to Ventricular Arrhythmia in Male Endurance Athletes
TUESDAY, July 22, 2025 -- Myocardial fibrosis is independently associated with the onset of ventricular arrhythmia in male veteran endurance athletes, according to a study...
Digital Model Based on Noninvasive Factors Shows Accuracy for Identifying IBD in Children
TUESDAY, July 22, 2025 -- A model based on noninvasive tests shows high accuracy as a digital tool for the rapid identification of children with inflammatory bowel disease (IBD)...
Prevalence of Extremely Severe Obesity Increasing in Children
TUESDAY, July 22, 2025 -- From 2008 to 2023, there was an increase in the prevalence of extremely severe obesity in children, especially among older adolescents and non-Hispanic...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.