ENDO: Osteoporosis Treatment Benefits Elderly Patients With Fragility Fracture
By Lori Solomon HealthDay Reporter
THURSDAY, July 17, 2025 -- Patients with osteoporosis who suffer a fragility fracture at age 80 years or older have better five-year outcomes if they receive treatment for osteoporosis, according to a study presented at ENDO 2025, the annual meeting of the Endocrine Society, held from July 12 to 15 in San Francisco.
Gianina Flocco, M.D., from the Cleveland Clinic, and colleagues used the TriNextX health research database to identify patients diagnosed with osteoporosis who suffered a fragility fracture at age 80 years or older. The analysis in this observational study included 44,338 matched pairs of patients who were treated with bisphosphonates, denosumab, raloxifene, or teriparatide and those who did not receive any of these treatments.
The researchers found that after five years of follow-up, the patients who suffered an osteoporotic fracture and received subsequent osteoporosis treatment had a lower incidence of hospitalizations (18,142 versus 20,385 patients; odds ratio, 0.814) and experienced lower all-cause mortality (11,073 versus 12,479 patients; odds ratio, 0.850).
"The results of our study support the need to enhance the individualized initiation of treatment of osteoporosis, even in people who are older than 80," Flocco said in a statement. "Treating people to reduce the burden of osteoporosis complications, like fractures leading to disability or death, would play a significant role in improving health span in the growing older population."
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted July 2025
Read this next
Long-Term Obesity Linked to Expression of Aging Biomarkers
THURSDAY, July 17, 2025 -- Long-term obesity is associated with the expression of biomarkers denoting antagonistic and integrative aging hallmarks in adults aged 28 to 31 years...
Cerebroplacental Ratio Better Guides Delivery With Perceived Less Fetal Movement
THURSDAY, July 17, 2025 -- An additional ultrasound measurement to assess resistance in fetal blood vessels can improve the decision of whether to expedite birth when a woman in...
Mediterranean, Plant-Based Diets Could Lower Risk for Constipation
THURSDAY, July 17, 2025 -- Dietary patterns emphasizing plant-based foods and healthy fats may protect against constipation, according to a study published online July 2...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.