Skip to main content

Early-Life Ozone Exposure Linked to Asthma, Wheeze at 4 to 6 Years Old

By Elana Gotkine HealthDay Reporter

Medically reviewed by Carmen Pope, BPharm. Last updated on April 3, 2025.

via HealthDay

THURSDAY, April 3, 2025 -- Early-life ozone (O3) exposure is associated with asthma and wheeze outcomes at 4 to 6 years of age, according to a study published online April 2 in JAMA Network Open.

Logan C. Dearborn, M.P.H., from the University of Washington in Seattle, and colleagues examined the associations between ambient O3 and subsequent asthma and wheeze outcomes -- independently and in mixture with fine particulate matter and nitrogen dioxide -- in a pooled multisite analysis across six U.S. cities.

The analytic sample included 1,188 participants. The mean O3 concentration was 26.1 parts per billion (ppb) in the first two years of life. The researchers found that 148 children had current asthma and 190 had current wheeze (12.3 and 15.8 percent, respectively) at age 4 to 6 years. Per 2 ppb higher O3 concentration, the odds ratios were 1.31 and 1.30 for current asthma and current wheeze, respectively, at age 4 to 6 years; for outcomes at 8 to 9 years and for sensitivity covariate adjustment, the associations were null. Higher exposure to O3 in mixture was associated with current asthma and wheeze in early childhood in Bayesian kernel machine regression.

"This analysis underscores the importance of better understanding the role of early-life exposure to ambient O3 in addressing risk factors for pediatric asthma in the U.S.," the authors write.

Abstract/Full Text

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.

Read this next

Coal Coking Plant Closure Tied to Immediate and Long-Term Respiratory Health Benefits

WEDNESDAY, July 30, 2025 -- Reductions in fossil fuel-related air pollution are linked to both short- and long-term lung health benefits for nearby residents, according to a study...

Illness Expectations Tied to Asthma Outcomes

WEDNESDAY, July 16, 2025 -- Illness expectations may be meaningfully associated with asthma symptoms and respiratory function, according to a study published online in the June...

Moderate-to-Severe Asthma Up for Female Permanent Night Shift Workers

THURSDAY, June 26, 2025 -- Female permanent night shift workers have higher odds of moderate-to-severe asthma than female day workers, but this relationship is not seen in men...

More news resources

Subscribe to our newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.