Drop in Mental Health Scores Seen With Primary Open-Angle Glaucoma Diagnosis
By Elana Gotkine HealthDay Reporter
MONDAY, June 9, 2025 -- Diagnosis of primary open-angle glaucoma (POAG) is associated with a reduction in mental health scores, according to a study published online June 5 in JAMA Ophthalmology.
Mae O. Gordon, Ph.D., from the Washington University School of Medicine in St. Louis, and colleagues conducted a post-hoc analysis of prospective data from the Ocular Hypertension Treatment Study (OHTS) phase 1 and 2 among all participants with ocular hypertension to examine whether mental health status as assessed by the National Eye Institute Visual Function Questionnaire-25 (VFQ) decreases after diagnosis of POAG. Participants completed a VFQ within two years before and within two years after POAG diagnosis. Controls were propensity-matched participants with ocular hypertension who did not develop POAG during the same period.
Fifty participants developed POAG and met the criteria for inclusion; they were matched to 100 OHTS control participants who did not develop POAG. The researchers found that the mean pre-POAG and post-POAG VFQ mental health scores were 94.5 and 88.0, respectively, among participants who developed POAG, for a mean change of −6.5. The mean preperiod and postperiod VFQ mental health scores in the matched control group were 93.3 and 92.6, respectively, for a mean change of −0.7. The mean difference in pre- and post-VFQ mental health scores was −5.8 between the POAG and control groups.
"As advances in technology enable earlier diagnosis of POAG, the impact of POAG diagnosis itself on mental health becomes increasingly relevant," the authors write.
Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted June 2025
Read this next
Late-Life Mood Disorders May Indicate Predisposition to Dementia
MONDAY, June 30, 2025 -- Alzheimer disease (AD) and diverse non-AD tau pathologies may contribute to late-life mood disorders (LLMDs), according to a study published online June 9...
Addictive Screen Use Tied to Suicidal Behaviors in Early Adolescence
FRIDAY, June 27, 2025 -- Both high and increasing addictive screen use trajectories are associated with suicidal behaviors and worse mental health in early adolescence, according...
Telehealth Intervention Beneficial for Seniors With Metastatic Cancer
WEDNESDAY, June 25, 2025 -- The telehealth-administered Geriatric Assessment–Guided Intervention (GAIN-S) improves physical function, mood, quality of life, and prognostic...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.