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Don't Sweat The Weight — Healthy Eating Helps Your Heart Regardless

Medically reviewed by Carmen Pope, BPharm. Last updated on June 9, 2025.

By Dennis Thompson HealthDay Reporter

MONDAY, June 9, 2025 — Don’t get frustrated if switching to a healthy diet doesn’t result in any weight loss – your heart is thanking you nonetheless, a new study says.

Even without weight loss, people who adopted a healthy diet received a significant boost to their heart health, researchers reported June 5 in the European Journal of Preventive Cardiology.

These included an increase in “good” HDL cholesterol, lower levels of the hunger hormone leptin, and less belly fat putting pressure on internal organs, researchers report.

“We have been conditioned to equate weight loss with health, and weight loss-resistant individuals are often labeled as failures,” said lead researcher Anat Yaskolka Meir, a postdoctoral research fellow in epidemiology at Harvard T.H. Chan School of Public Health.

“Our findings reframe how we define clinical success,” Yasolka Meir said in a news release. “People who do not lose weight can improve their metabolism and reduce their long-term risk for disease. That’s a message of hope, not failure.”

For the study, researchers analyzed data from 761 people with obesity in Israel who participated in three landmark workplace-based clinical trials involving nutrition.

In each trial, people were randomly assigned to adopt and stick with healthy diets for between 18 and 24 months.

Results showed that nearly one-third of the participants did not lose any weight.

However, people who were resistant to weight loss still showed many of the same improvements as those who did drop pounds, researchers said.

“These are deep metabolic shifts with real cardiometabolic consequences,” Yaskolka Meir said. “Our study showed that a healthy diet works, even when weight doesn’t shift.”

The study also found 12 specific sites where a person’s genetics can strongly predict their ability to lose weight.

“This novel finding shows that some people may be biologically wired to respond differently to the same diet,” senior researcher Iris Shai, an adjunct professor of nutrition at the Harvard T.H. Chan School, said in a news release.

“This isn’t just about willpower or discipline — it’s about biology,” Shai said. “And now we’re getting close to understanding it.”

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.

Posted June 2025

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