• All News
• Consumer
• Pro
• New Drugs
• Pipeline
• Clinical Trials
• FDA Alerts

Concussions Slow Brain Activity in High School Football Players

Medically reviewed by Carmen Pope, BPharm. Last updated on Nov 26, 2024.

By Ernie Mundell HealthDay Reporter

TUESDAY, Nov. 26, 2024 (HeathDay News) -- A potentially important form of brain signaling appears to be affected whenever concussion strikes, according to new research involving high school football players.

“This study is important because it provides insight into both the mechanisms and the clinical implications of concussion in the maturing adolescent brain,” said study co-lead author Alex Wiesman, assistant professor at Simon Fraser University in Burnaby, British Columbia, Canada.

He and his colleagues are slated to present their findings next week in Chicago at the annual meeting of the Radiological Society of North America (RSNA).

As the researchers explained, multiple concussion studies have already examined the effects of head injury on what's known as periodic or "rhythmic" brain signaling, which is crucial to attention, movement or sensory processing.

But much less has been known about non-rhythmic brain signaling.

“Most previous neuroscience research has focused on rhythmic brain signaling, which is also called periodic neurophysiology,” explained study lead author Kevin Yu, a neuroscience student at Wake Forest University School of Medicine in Winston-Salem, N.C. “On the other hand, aperiodic neurophysiology refers to brain signals that are not rhythmic.”

For a long time, neurologists haven't paid a lot of attention to aperiodic signaling, considering it mere "background noise" in the brain. But that perspective is beginning to change.

“While it’s often overlooked, aperiodic activity is important because it reflects brain cortical excitability,” said study senior author Dr. Christopher Whitlow, professor and chair of radiology at Wake Forest.

It's now thought that cortical excitability could be a key player in how brain cells respond to stimulation. It might also play a role in memory, information processing, decision making, motor control, wakefulness and sleep, the researchers said.

In the new study, the research team examined neurological data on 91 high school football players, of whom 10 were diagnosed with a concussion. They compared players' pre- and post-season magnetoencephalography (MEG) data, a technology that tracks brain signaling.

The most important finding: Players who had suffered a concussion showed a definite "slowing" of their aperoidic brain activity, compared to concussion-free players.

Those slowdowns were reflected in poorer scores on tests the injured played took to gauge their cognition, the researchers said.

However, the research is still early, Weisman stressed.

“Reduced excitability is conceptually a very different brain activity change than altered rhythms," he said, "and means that a clear next step for this work is to see whether these changes are related to effects of concussion on the brain’s chemistry."

For now, the findings support guidelines that mandate that any player take the necessary time to fully recover from a concussion before returning to play.

“It highlights the importance of monitoring kids carefully after any head injury and taking concussions seriously," Whitlow said.

Because these findings were presented at a medical meeting, they should be considered preliminary until published in a peer-reviewed journal.

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.

Posted November 2024

More news resources

• FDA Medwatch Drug Alerts
• Daily MedNews
• News for Health Professionals
• New Drug Approvals
• New Drug Applications
• Drug Shortages
• Clinical Trial Results
• Generic Drug Approvals

Subscribe to our newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.