Community-Level Social, Environmental Factors Tied to Mild Cognitive Impairment
By Lori Solomon HealthDay Reporter
WEDNESDAY, Nov. 27, 2024 -- Several community-wide social and environmental factors are associated with the onset of mild cognitive impairment (MCI) in older dementia-free individuals, according to a study published online Nov. 20 in the Journal of the American Geriatrics Society.
Mary Ganguli, M.D., M.P.H., from the University of Pittsburgh School of Medicine, and colleagues examined associations between community-wide social determinants of health and MCI. The analysis included data from 2,830 dementia-free individuals (aged 65 years and older).
The researchers found that unadjusted models revealed higher odds of MCI with higher Area Deprivation Index scores (odds ratio [OR], 1.01), higher fine particulate matter (PM2.5; OR, 1.16), higher homicide rates (OR, 1.007), lesser greenspace (OR, 0.99), and Southern state schooling (OR, 2.06). When adjusting for age, race, sex, and educational level, the Area Deprivation Index remained a significant risk factor. However, for PM2.5 and Southern state schooling, there were significant interactions with race; Black participants were more strongly affected than White participants.
"In this cohort, several community-wide social/environmental factors were associated with MCI," the authors write. "While clinicians should continue to encourage older adults to modify their individual risk factors, policy changes are needed to mitigate social determinants of health in the community."
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.
Posted November 2024
Read this next
Shorter Leukocyte Telomere Length Linked to Higher Incidence of Age-Related Brain Diseases
THURSDAY, June 12, 2025 -- Individuals with shorter leukocyte telomere length (LTL) have a higher incidence of stroke, dementia, and late-life depression (LLD), individually and...
Epilepsy More Common With Frontotemporal Dementia
TUESDAY, June 10, 2025 -- Epilepsy is more common among those with frontotemporal dementia (FTD) than among people with Alzheimer disease (AD) or healthy controls, according to a...
Preoperative Blood Pressure Strategies Yield Similar Postoperative Cognitive Results
FRIDAY, June 6, 2025 -- For patients undergoing noncardiac surgery, neurocognitive outcomes do not differ with hypotension-avoidance and hypertension-avoidance strategies...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.