Bronchodilator Responsiveness Positivity More Likely in Morning
By Elana Gotkine HealthDay Reporter
WEDNESDAY, March 12, 2025 -- Patients are more likely to have positive bronchodilator responsiveness in the morning and in winter months, according to a study published online March 11 in Thorax.
Ben Knox-Brown, Ph.D., from the Royal Papworth Hospital NHS Foundation Trust in Cambridge, England, and colleagues examined the association between time of day and season of testing on the level of bronchodilator responsiveness in a population of 1,620 patients.
The researchers found that the odds of a positive bronchodilator response decreased by 8 percent per one-hour increment in the working day (odds ratio, 0.92). When time of day was dichotomized into morning and afternoon periods, a similar effect was seen, with reduced odds of responsiveness in the afternoon (odds ratio, 0.68). The impact of time of day was only seen in those referred for asthma/query asthma, while no association was seen for those referred for other reasons. Compared with the rest of the year, bronchodilator responsiveness was more common in winter months.
"These findings suggest that performing diagnostic testing when patients are most symptomatic, that is, in the morning, may improve diagnostic testing," the authors write. "This also reinforces the need to document the timing of spirometry testing whenever possible, and that repeat testing should be done at the same time of day."
One author disclosed financial ties to ndd Medical Technologies.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted March 2025
Read this next
Moderate-to-Severe Asthma Up for Female Permanent Night Shift Workers
THURSDAY, June 26, 2025 -- Female permanent night shift workers have higher odds of moderate-to-severe asthma than female day workers, but this relationship is not seen in men...
Passive Digital Marker Can Identify Childhood Asthma Risk
TUESDAY, June 17, 2025 -- It is feasible to use electronic health record (EHR) data in the Pediatric Asthma Risk Score (PARS) to accurately predict childhood asthma risk...
Cardiorespiratory Effects of Smoke Fine Particulate Matter From Wildfires Can Persist for Months
THURSDAY, June 5, 2025 -- The cardiorespiratory effects of smoke fine particulate matter (PM2.5), a primary wildfire emission that can spike for months after a wildfire begins...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.