2023 to 2024 COVID-19 Vaccine Provided Additional Effectiveness
By Elana Gotkine HealthDay Reporter
WEDNESDAY, July 2, 2025 -- The 2023 to 2024 COVID-19 vaccine provided additional effectiveness against medically attended COVID-19, according to a study published online June 24 in JAMA Network Open.
Ruth Link-Gelles, Ph.D., M.P.H., from the U.S. Centers for Disease Control and Prevention in Atlanta, and colleagues conducted a case-control study to examine the vaccine effectiveness (VE) of 2023 to 2024 (monovalent XBB.1.5) COVID-19 vaccines against COVID-19-associated emergency department (ED) and urgent care (UC) encounters, hospitalizations, and critical illness among adults during periods of Omicron XBB and JN.1 predominance.
The researchers found that 37,096 (11 percent) of 345,639 eligible ED and UC encounters in immunocompetent adults with COVID-19-like illness and available test results had a positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) result. During seven to 299 days after vaccination, VE against COVID-19-associated ED and UC encounters was 24 percent. Nine percent of 111,931 eligible hospitalizations in immunocompetent adults with COVID-19-like illness and available test results had a positive SARS-CoV-2 test result. VE was 29 and 48 percent against COVID-19-associated hospitalization and critical illness, respectively, during seven to 299 days after vaccination. VE was highest at seven to 59 days after vaccination (VE: 49, 51, and 68 percent against ED and UC encounters, hospitalizations, and critical illness, respectively) and then waned (VE at 180 to 299 days after vaccination, −7, −4, and 16 percent, respectively).
"The 2023-2024 COVID-19 vaccines were associated with additional protection against COVID-19-associated ED and UC encounters, hospitalization, and critical illness beyond existing protection provided by prior vaccination or SARS-CoV-2 infection," the authors write.
Several authors disclosed ties to the pharmaceutical industry.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted July 2025
Further Support and Information on COVID-19
Read this next
Helping Others Linked to Higher Level of Cognitive Function
THURSDAY, Aug. 21, 2025 -- Helping others, both via formal volunteering and informal helping, is associated with higher levels of cognitive function and slower cognitive decline...
TAR-200 Monotherapy Promising for BCG-Unresponsive Bladder Cancer
THURSDAY, Aug. 21, 2025 -- For patients with Bacillus Calmette-Guérin (BCG)-unresponsive high-risk non-muscle-invasive bladder cancer (NMIBC), an intravesical...
Work-Related Income Drops for Parents of Children Diagnosed With Type 1 Diabetes
THURSDAY, Aug. 21, 2025 -- Work-related income decreases sharply for mothers and fathers of children diagnosed with type 1 diabetes, with similar effects across sociodemographic...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.