Skip to main content

2011 to 2023 Saw Increase in Early Adult Mortality in the United States

Medically reviewed by Carmen Pope, BPharm. Last updated on Feb 11, 2025.

By Elana Gotkine HealthDay Reporter

TUESDAY, Feb. 11, 2025 -- From 2011 to 2023, there was an increase in early adult mortality in the United States, with further acceleration seen during the COVID-19 pandemic, according to a research letter published online Jan. 31 in JAMA Network Open.

Elizabeth Wrigley-Field, Ph.D., from the University of Minnesota in Minneapolis, and colleagues calculated monthly mortality rates using cause-specific death counts for adults aged 25 to 44 years between 1999 and 2023.

The study analyzed 3,392,364 deaths among the full U.S. population aged 25 to 44 years from 1999 to 2023. Compared with extrapolations of pre-2011 trends, mortality increases across most causes of death produced substantial excess deaths. In 2019, early adult excess mortality was 34.6 percent higher than expected, with further acceleration during the COVID-19 pandemic. All-cause excess mortality was nearly three times higher in 2021 than 2019 (116.2 versus 41.7 deaths per 100,000 population). Excess mortality decreased in 2023 to approximately midway between 2019 and 2021 levels (79.1 deaths per 100,000 population). In 2023, early adult mortality was 70.0 percent higher than it would have been had pre-2011 trends continued, with 71,124 excess deaths. In 2023, drug poisoning, residual natural cause category, transport-related deaths, alcohol-related deaths, and homicide accounted for almost three-quarters of early adult excess mortality (31.8, 16.0, 14.1, 8.5, and 8.2 percent, respectively).

"Increases in early adult mortality can signal population risks that may become more pronounced as these cohorts age. These results suggest the possibility of a worsening mortality crisis unless these trends are reversed," the authors write.

Abstract/Full Text

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2025 HealthDay. All rights reserved.

Read this next

Caregiver Concern Can Be Key to Identifying Critical Illness in Hospitalized Children

FRIDAY, June 6, 2025 -- For pediatric patients presenting to a hospital, caregiver concern for clinical deterioration is associated with critical illness, according to a study...

Boarding Common for Pediatric Mental Health Emergency Department Visits

FRIDAY, June 6, 2025 -- One-third of pediatric mental health emergency department visits resulting in admission or transfer exceeded 12 hours, according to a study published in...

Atypical BMI Trajectory Detectable in Children as Early as Age 3.5 Years

THURSDAY, June 5, 2025 -- Children on the path to obesity can be detected as early as age 3.5 years, according to a study published online May 22 in JAMA Network Open. Chang...

More news resources

Subscribe to our newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.