What is Emflaza?
Emflaza is a steroid that is used to treat Duchenne muscular dystrophy in adults and children at least 2 years old.
Emflaza is not a cure for muscular dystrophy, but Emflaza may improve muscle strength and slow the progression of disability.
Emflaza may also be used for purposes not listed in this medication guide.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
You should not use Emflaza if you are allergic to it.
Emflaza should not be given to a child younger than 2 years old. This medicine oral suspension (liquid) contains an ingredient that can cause serious side effects or death in very young or premature babies.
Tell your doctor if you have ever had:
any type of bacterial, fungal, viral, or parasite infection;
heart problems, high blood pressure;
a stroke or blood clot;
liver disease (especially hepatitis B);
a stomach or intestinal disorder;
a colostomy or ileostomy;
cataracts, glaucoma, or herpes infection of the eyes;
a nerve-muscle disorder, such as myasthenia gravis;
low bone mineral density; or
a problem with your thyroid, pituitary gland, or adrenal gland.
You should be current on all vaccines. Tell your doctor if you have recently received a vaccine or if you are scheduled for a booster dose.
Long-term use of steroids may lead to bone loss (osteoporosis), especially if you smoke, if you do not exercise, if you do not get enough vitamin D or calcium in your diet, or if you have a family history of osteoporosis.
Taking Emflaza during early pregnancy may increase the risk of cleft lip and palate in a newborn. Tell your doctor if you are pregnant or plan to become pregnant.
Taking Emflaza at any time during pregnancy may affect adrenal gland hormones in the newborn baby. Tell your doctor if your baby has symptoms such as dry skin, weakness, feeding problems, or vomiting.
It may not be safe to breastfeed while using Emflaza. Ask your doctor about any risk.
How should I take Emflaza?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
You may take Emflaza with or without food.
You may need to take multiple tablets of different strengths to make up your correct dose. Follow your doctor's dosing instructions very carefully.
If you cannot swallow a tablet whole, crush it and sprinkle the medicine into a spoonful of applesauce. Swallow the mixture right away without chewing. Do not save it for later use.
Shake the oral suspension (liquid) before you measure a dose. Use only the dosing syringe provided (not a kitchen spoon) to measure your dose. Mix your measured dose with 3 to 4 ounces of milk or fruit juice (but not grapefruit juice). Drink this mixture right away and do not save it for later.
Emflaza doses are based on weight (especially in children and teenagers). Your dose needs may change if you gain or lose weight.
Emflaza can weaken (suppress) your immune system, and you may get an infection more easily. You may need frequent medical tests. Your vision and bone mineral density may also need to be checked.
Tell your doctor if you have recently traveled. Certain infections are more common in certain parts of the world, and you may have been exposed during travel.
If you've ever had hepatitis B or if you are a carrier of hepatitis B, using Emflaza can cause this virus to become active or get worse. You may need frequent liver function tests.
If you need surgery, tell the surgeon ahead of time that you are using Emflaza.
Store at room temperature away from moisture and heat.
Throw away any Emflaza liquid that has not been used within 1 month after you first opened the bottle.
You should not stop using Emflaza suddenly. Follow your doctor's instructions about tapering your dose. You may need to restart this medicine if you are under stress or if you have a medical emergency.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking Emflaza?
Grapefruit and grapefruit juice may interact with Emflaza and lead to unwanted side effects. Avoid the use of grapefruit products while taking this medicine.
While taking Emflaza and for at least 4 to 6 weeks before you start taking it: Do not receive a "live" vaccine or you could develop a serious infection.
Ask your doctor before getting any vaccine.
Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chickenpox or measles. These conditions can be serious or even fatal in people who are using steroid medicine.
Emflaza side effects
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Call your doctor at once if you have:
fever, chills, sore throat, weakness;
severe or ongoing diarrhea;
any skin rash, no matter how mild;
blurred vision, tunnel vision, eye pain, or seeing halos around lights;
swelling in your hands, feet, or lower legs;
severe muscle weakness;
increased adrenal gland hormones--weight gain in your face and upper back, slow wound healing, skin discoloration, acne, thinning skin, increased body hair, tiredness, mood changes, menstrual changes, sexual changes;
high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or
Emflaza can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using Emflaza.
Common side effects may include:
increased growth of body hair;
cold symptoms such as stuffy nose, sneezing, sore throat, cough;
frequent urge to urinate; or
changes in the shape or location of body fat (especially in your face and back).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Emflaza?
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
When you start or stop taking Emflaza, your doctor may need to adjust the doses of any other medicines you take on a regular basis.
Many drugs can affect Emflaza. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.
Frequently asked questions
More about Emflaza (deflazacort)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Pricing & Coupons
- En Español
- Drug class: glucocorticoids
- FDA Approval History
Related treatment guides
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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