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How long does Plavix stay in the body once I stop taking it. How much Plavix is too much?

Medically reviewed by Drugs.com Last updated on Oct 18, 2018.

Official Answer

by Drugs.com

Plavix should be cleared from your system in about 33 hours.
After a single, oral dose of 75 mg, Plavix (clopidogrel) has a half-life of approximately 6 hours. It takes 5.5 x half-life of a medicine for it to be out of one's system, therefore Plavix should be eliminated from your system in 5.5 x 6 = 33 hours.

However other factors to consider include:
1. How much and how often you have taken the drug.
2. Your metabolic rate – a slower metabolism will increase the time a drug remains in your system.
3. Your age and health – older age and poor health will generally increase the time the drug stays in your system.
4. Body mass – generally the bigger you are the longer a drug will remain in your system.

The recommended daily dose of Plavix is 75 milligrams once a day. To give people with unstable angina an extra boost, their first dose is usually increased to 300 milligrams. Anything more than this is too much.

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