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Prothrombin Complex, Human


Ph. Eur.

ATC (Anatomical Therapeutic Chemical Classification)


CAS registry number (Chemical Abstracts Service)


Therapeutic Categories

Hemostatic agent

Blood coagulation factors (complex) substitute

Chemical Name

Human prothrombin complex is a plasma protein fraction containing blood coagulation factor IX togehter with variable amounts of coagulation factors II, VII and X

Foreign Names

  • Prothrombinum multiplex humanum (Latin)
  • Prothrombinkomplex vom Menschen (German)
  • Complexe prothrombique humain (French)

Generic Names

  • Factor IX Fraction (OS: BAN)
  • Facteurs de la coagulation IX, II, VII et X en association (IS)
  • Factor IX Complex (IS: Human)
  • Gerinnungsfaktoren IX, II, VII und X in Kombination (IS)
  • PCC (IS)
  • PPSB (IS)
  • Prothrombin complex concentrate (IS)
  • Complexe prothrombique humain (PH: Ph. Eur. 8)
  • Dried Prothrombin Complex (PH: BP 2016)
  • Factor IX Complex (PH: USP 38)
  • Human prothrombin complex (PH: Ph. Eur. 8)
  • Prothrombinkomplex vom Menschen (PH: Ph. Eur. 8)
  • Prothrombinum multiplex humanum (PH: Ph. Eur. 8)

Brand Names

  • Beriplex P/N
    CSL Behring, Netherlands; CSL Behring, Poland; CSL Behring, Tunisia
  • Beriplex P/N (Prothrombin Complex, Human and Protein S, Human; Protein C, Human)
    CSL Behring, Austria; CSL Behring, Switzerland; CSL Behring, Germany; CSL Behring, Spain; CSL Behring UK, United Kingdom
  • Cofact
    Biotest Pharma, Germany; Centurion Pharma, Turkey; Sanquin, Austria; Sanquin, Finland; Sanquin, Netherlands
  • Confidex
    CSL Behring, Finland; CSL Behring, Italy; CSL Behring, Sweden
  • Confidex (Prothrombin Complex, Human and Protein C, Human; + Protein S, Human)
    CSL Behring, Belgium; CSL Behring, Norway
  • Kcentra
    CSL Behring, United States
  • Ocplex
    Octapharma, Sweden
  • Octaplex
    Jana, Croatia (Hrvatska); Octapharma, Estonia; Octapharma, Poland; Octapharma, Tunisia
  • Octaplex (Prothrombin Complex, Human and Protein S, Human, + Protein C, Human)
    Octapharma, Bosnia & Herzegowina; Octapharma, Belgium; Octapharma, Spain; Octapharma, United Kingdom; Octapharma, Norway; Octapharma Pharmazeutika, Austria
  • Octaplex 1000 (Prothrombin Complex, Human and Protein S, Human, + Protein C, Human)
    Octapharma, Switzerland
  • Octaplex 500 (Prothrombin Complex, Human and Protein S, Human, + Protein C, Human)
    Laboratorio Bago, Chile; Octapharma, Switzerland; Octapharma, Germany; Octapharma, Finland
  • PPSB S.D.
    CAF-DCF, Belgium
  • PPSB-HT Nichiyaku
    Nihon Seiyaku, Japan
  • Profilnine
    Grifols, Bangladesh; Grifols, Thailand
  • Profilnine SD
    Grifols, Hong Kong; Grifols, Malaysia; Grifols, Philippines; Grifols, Taiwan
  • ProthoRAAS
    Shanghai Raas, Georgia
  • Prothrombin Complex Octapharm
    Octapharma, Hungary
  • Prothrombinex-HT
    CSL Behring, Hong Kong
  • Prothromplex
    Baxter, Estonia; Baxter, Finland; Baxter, Sweden; Baxter, Slovakia
  • Prothromplex (Prothrombin Complex, Human and Protein C, Human, + Heparin, + Antithrombin III)
    Baxter, Norway
  • Prothromplex Immuno Tim4 (Prothrombin Complex, Human and Protein C, Human, + Heparin, + Antithrombin III)
    Baxter, Spain
  • Prothromplex NF
    Baxalta, Switzerland; Baxter, Germany
  • Prothromplex Total
    Baxter, Austria; Baxter, Hungary; Baxter, Tunisia
  • Prothromplex Total NF
    Baxter, Bulgaria; Baxter, Poland
  • Protromplex TIM 3
    Baxter-RM, Italy
  • Pushu Laishi
    Shanghai Raas, China
  • TachoSil (Prothrombin Complex, Human and Fibrinogen, Human)
    Al Hikma, Oman
  • Uman Complex
    Kedrion, Italy
  • Uman-Complex D. I.
    Kedrion, Bulgaria


BANBritish Approved Name
ISInofficial Synonym
OSOfficial Synonym
PHPharmacopoeia Name
Ph. Eur.European Pharmacopoeia

Further information on drug naming conventions: International Nonproprietary Names.

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