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In the US, Icatibant (icatibant systemic) is a member of the drug class miscellaneous cardiovascular agents and is used to treat Hereditary Angioedema.

US matches:



ATC (Anatomical Therapeutic Chemical Classification)


CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Categories

Treatment of hereditary angioedema

Bradykinin receptor B2 antagonist

Chemical Names

(R)-arginyl-(S)-arginyl-(S)-prolyl-(2S,4R)-(4-hydroxyprolyl)glycyl-(S)-[3-(2-tienyl)alanyl]-(S)-seryl-(R)-[(1,2,3,4-tetrahydro-3-isochinolyl)carbonyl]-(2S,3aS,7aS)-[(hexahydro-2-indolin-3-yl)carbonyl]-(S)-arginin (IUPAC)

(R)-Arginyl-(S)-arginyl-(S)-prolyl-(2S,4R)-(4-hydroxyprolyl)glycyl-(S)-[3-(2-tienyl)alanyl]-(S)-seryl-(R)-[(1,2,3,4-tetrahydro-3-isoquinolyl)carbonyl]-(2S,3aS,7aS)-[(hexahydro-2-indolinyl)carbonyl]-(S)-arginine (WHO)


L-arginine, D-arginyl-L-arginyl-L-prolyl-trans-4-hydroxy-L-prolylglycyl-3-(2-tienyl)-L-alanyl-L-seryl-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2α,3abeta,7abeta)-octahydro-1H-indole-2-carbonyl- (CAS)

Foreign Names

  • Icatibantum (Latin)
  • Icatibant (German)
  • Icatibant (French)
  • Icatibanto (Spanish)

Generic Names

  • Icatibant (OS: BAN)
  • HOE 140 (IS)
  • Hoec (IS)
  • Hoechst 140 (IS)
  • JE-049 (Jerini) (IS)
  • Icatibant Acetate (OS: USAN, BANM)

Brand Names

  • Firazyr
    Shire, Brazil; Shire, Finland; Shire, Norway; Shire, New Zealand; Shire, Poland; Shire, Romania; Shire Denmark, Denmark; Shire Human Genetic Therapies, Serbia; Shire Orphan Therapien GmbH, Greece; Shire Orphan Therapies GmbH, Croatia (Hrvatska); Shire, Australia; Shire, Czech Republic; Shire, Estonia; Shire, Spain; Shire, France; Shire, Lithuania; Shire, United States; Shire Argentina, Argentina; Shire Colombia, Colombia; Shire Deutschland, Germany; Shire Human Genetic Therapies, United Kingdom; Shire Human Genetic Therapies, Sweden; Shire Orphan, Slovenia; Shire Orphan Therapies, Belgium; Shire Pharma, Canada; Shire Pharmaceuticals Ireland, Ireland
  • Firazyr 30 mg
    Shire Pharmaceutical Contracts Ltd., Hungary
  • Firazyr 30mg
    Shire, Israel; Shire Orphan, Austria
  • Firazyr 30mg/3ml
    Shire, Switzerland; Shire, Luxembourg


BANBritish Approved Name
BANMBritish Approved Name (Modified)
CASChemical Abstracts Service
IUPACInternational Union of Pure and Applied Chemistry
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Further information on drug naming conventions: International Nonproprietary Names.

Important Notice: The international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Further information

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