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In the US, Icatibant (icatibant systemic) is a member of the drug class miscellaneous cardiovascular agents and is used to treat Hereditary Angioedema.

US matches:



ATC (Anatomical Therapeutic Chemical Classification)


CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Categories

Treatment of hereditary angioedema

Bradykinin receptor B2 antagonist

Chemical Names

(R)-arginyl-(S)-arginyl-(S)-prolyl-(2S,4R)-(4-hydroxyprolyl)glycyl-(S)-[3-(2-tienyl)alanyl]-(S)-seryl-(R)-[(1,2,3,4-tetrahydro-3-isochinolyl)carbonyl]-(2S,3aS,7aS)-[(hexahydro-2-indolin-3-yl)carbonyl]-(S)-arginin (IUPAC)

(R)-Arginyl-(S)-arginyl-(S)-prolyl-(2S,4R)-(4-hydroxyprolyl)glycyl-(S)-[3-(2-tienyl)alanyl]-(S)-seryl-(R)-[(1,2,3,4-tetrahydro-3-isoquinolyl)carbonyl]-(2S,3aS,7aS)-[(hexahydro-2-indolinyl)carbonyl]-(S)-arginine (WHO)


L-arginine, D-arginyl-L-arginyl-L-prolyl-trans-4-hydroxy-L-prolylglycyl-3-(2-tienyl)-L-alanyl-L-seryl-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2α,3abeta,7abeta)-octahydro-1H-indole-2-carbonyl- (CAS)

Foreign Names

  • Icatibantum (Latin)
  • Icatibant (German)
  • Icatibant (French)
  • Icatibanto (Spanish)

Generic Names

  • Icatibant (OS: BAN)
  • HOE 140 (IS)
  • Hoec (IS)
  • Hoechst 140 (IS)
  • JE-049 (IS: Jerini)
  • Icatibant Acetate (OS: USAN, BANM)

Brand Names

  • Firazyr
    Shire, Denmark; Shire, Greece; Shire, Norway; Shire, Poland; Shire Human Genetic Therapies AB, Portugal; Solpharm, Croatia (Hrvatska); DRAC, Switzerland; Shire, Australia; Shire, Belgium; Shire, Canada; Shire, Czech Republic; Shire, Germany; Shire, Spain; Shire, Finland; Shire, France; Shire, Israel; Shire, Lithuania; Shire, United States; Shire Human Genetic Therapies, United Kingdom; Shire Human Genetic Therapies, Sweden; Shire Italia, Italy; Shire Orphan, Austria; Shire Orphan, Slovenia; Shire Pharmaceutical Contracts Ltd., Hungary; Shire Pharmaceuticals Ireland, Ireland


BANBritish Approved Name
BANMBritish Approved Name (Modified)
CASChemical Abstracts Service
IUPACInternational Union of Pure and Applied Chemistry
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Further information on drug naming conventions: International Nonproprietary Names.

Important Notice: The international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Further information

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