Icatibant
In the US, Icatibant (icatibant systemic) is a member of the drug class miscellaneous cardiovascular agents and is used to treat Hereditary Angioedema.
US matches:
Scheme
Rec.INN
ATC (Anatomical Therapeutic Chemical Classification)
B06AC02
CAS registry number (Chemical Abstracts Service)
0130308-48-4
Chemical Formula
C59-H89-N19-O13-S
Molecular Weight
1304
Therapeutic Categories
Treatment of hereditary angioedema
Bradykinin receptor B2 antagonist
Chemical Names
(R)-arginyl-(S)-arginyl-(S)-prolyl-(2S,4R)-(4-hydroxyprolyl)glycyl-(S)-[3-(2-tienyl)alanyl]-(S)-seryl-(R)-[(1,2,3,4-tetrahydro-3-isochinolyl)carbonyl]-(2S,3aS,7aS)-[(hexahydro-2-indolin-3-yl)carbonyl]-(S)-arginin (IUPAC)
(R)-Arginyl-(S)-arginyl-(S)-prolyl-(2S,4R)-(4-hydroxyprolyl)glycyl-(S)-[3-(2-tienyl)alanyl]-(S)-seryl-(R)-[(1,2,3,4-tetrahydro-3-isoquinolyl)carbonyl]-(2S,3aS,7aS)-[(hexahydro-2-indolinyl)carbonyl]-(S)-arginine (WHO)
D-arginyl-L-arginyl-L-prolyl-trans-4-hydroxy-L-prolylglycyl-3-(2-tienyl)-L-alanyl-L-seryl-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2α,3abeta,7abeta)-octahydro-1H-indole-2-carbonyl-L-arginine
L-arginine, D-arginyl-L-arginyl-L-prolyl-trans-4-hydroxy-L-prolylglycyl-3-(2-tienyl)-L-alanyl-L-seryl-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2α,3abeta,7abeta)-octahydro-1H-indole-2-carbonyl- (CAS)
Foreign Names
- Icatibantum (Latin)
- Icatibant (German)
- Icatibant (French)
- Icatibanto (Spanish)
Generic Names
- Icatibant (OS: BAN)
- HOE 140 (IS)
- Hoec (IS)
- Hoechst 140 (IS)
- JE-049 (IS: Jerini)
- Icatibant Acetate (OS: USAN, BANM)
Brand Names
- Firazyr
Shire, Denmark; Shire, Greece; Shire, Norway; Shire, Poland; Shire Human Genetic Therapies AB, Portugal; Solpharm, Croatia (Hrvatska); DRAC, Switzerland; Shire, Australia; Shire, Belgium; Shire, Canada; Shire, Czech Republic; Shire, Germany; Shire, Spain; Shire, Finland; Shire, France; Shire, Israel; Shire, Lithuania; Shire, United States; Shire Human Genetic Therapies, United Kingdom; Shire Human Genetic Therapies, Sweden; Shire Italia, Italy; Shire Orphan, Austria; Shire Orphan, Slovenia; Shire Pharmaceutical Contracts Ltd., Hungary; Shire Pharmaceuticals Ireland, Ireland
Glossary
| Term | Definition |
|---|---|
| BAN | British Approved Name |
| BANM | British Approved Name (Modified) |
| CAS | Chemical Abstracts Service |
| IUPAC | International Union of Pure and Applied Chemistry |
| IS | Inofficial Synonym |
| OS | Official Synonym |
| Rec.INN | Recommended International Nonproprietary Name (World Health Organization) |
| USAN | United States Adopted Name |
| WHO | World Health Organization |
Further information on drug naming conventions: International Nonproprietary Names.
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