Drug Interaction Report

Talk to your doctor before using diphenhydrAMINE together with donepezil. Medications like diphenhydrAMINE may reduce the effectiveness of donepezil. In addition, patients with Alzheimer's disease or other dementia may be more likely to experience nervous system side effects of diphenhydrAMINE such as drowsiness, confusion, and mental impairment. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Ask your doctor before using diphenhydrAMINE together with ethanol (alcohol). Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking diphenhydrAMINE. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.