Drug Interaction Report
4 potential interactions and/or warnings found for the following 2 drugs:
- donepezil
- Leader Heartburn Relief (cimetidine)
Interactions between your drugs
cimetidine donepezil
Applies to: Leader Heartburn Relief (cimetidine), donepezil
Talk to your doctor before using cimetidine together with donepezil. Medications like cimetidine may reduce the effectiveness of donepezil. In addition, patients with Alzheimer's disease or other dementia may be more likely to experience nervous system side effects of cimetidine such as drowsiness, confusion, and mental impairment. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
cimetidine food
Applies to: Leader Heartburn Relief (cimetidine)
Information for this minor interaction is available on the professional version.
cimetidine food
Applies to: Leader Heartburn Relief (cimetidine)
Information for this minor interaction is available on the professional version.
cimetidine food
Applies to: Leader Heartburn Relief (cimetidine)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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