Drug Interaction Report

Ezogabine may increase the blood levels of DAUNOrubicin. This can increase the risk of side effects such as irregular heartbeat, heart failure, and impaired bone marrow function resulting in low numbers of different types of blood cells. You may also be more likely to develop anemia, bleeding problems, or infections due to low blood cell counts. Contact your doctor if you experience potential signs and symptoms of these conditions such as paleness, fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches, or other flu-like symptoms. You should seek immediate medical attention if you experience sudden, unexplained weight gain; swelling of the hands, ankles, or feet; chest pain; or difficulty breathing, as these may be indications of heart failure. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Alcohol can increase the blood levels of ezogabine and worsen side effects such as drowsiness, dizziness, nausea, constipation, difficulty urinating, blurred vision, memory impairment, and tremor. You should avoid or limit the use of alcohol while being treated with ezogabine. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Ezogabine may be taken with or without food. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.