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Drug Interaction Report

8 potential interactions and/or warnings found for the following 2 drugs:

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Interactions between your drugs

Moderate

famotidine lisdexamfetamine

Applies to: calcium carbonate / famotidine / magnesium hydroxide, Vyvanse (lisdexamfetamine)

Using famotidine together with lisdexamfetamine can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect. You may be more susceptible if you have a heart condition called congenital long QT syndrome, other cardiac diseases, conduction abnormalities, or electrolyte disturbances (for example, magnesium or potassium loss due to severe or prolonged diarrhea or vomiting). Talk to your doctor if you have any questions or concerns. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with these medications, whether together or alone. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

calcium carbonate lisdexamfetamine

Applies to: calcium carbonate / famotidine / magnesium hydroxide, Vyvanse (lisdexamfetamine)

Ask your doctor before using calcium carbonate together with lisdexamfetamine. Using these medications together can increase the absorption of lisdexamfetamine and may increase its effects. This can cause restlessness, tremor, rapid breathing, confusion, panic, aggressiveness, nausea, vomiting, diarrhea, an irregular heartbeat, and seizures. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

magnesium hydroxide lisdexamfetamine

Applies to: calcium carbonate / famotidine / magnesium hydroxide, Vyvanse (lisdexamfetamine)

Ask your doctor before using magnesium hydroxide together with lisdexamfetamine. Using these medications together can increase the absorption of lisdexamfetamine and may increase its effects. This can cause restlessness, tremor, rapid breathing, confusion, panic, aggressiveness, nausea, vomiting, diarrhea, an irregular heartbeat, and seizures. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

famotidine calcium carbonate

Applies to: calcium carbonate / famotidine / magnesium hydroxide, calcium carbonate / famotidine / magnesium hydroxide

Information for this minor interaction is available on the professional version.

Minor

famotidine magnesium hydroxide

Applies to: calcium carbonate / famotidine / magnesium hydroxide, calcium carbonate / famotidine / magnesium hydroxide

Information for this minor interaction is available on the professional version.

Drug and food interactions

Moderate

calcium carbonate food

Applies to: calcium carbonate / famotidine / magnesium hydroxide

Calcium absorption may be increased by taking it with food. However, foods high in oxalic acid (spinach or rhubarb), or phytic acid (bran and whole grains) may decrease calcium absorption. Calcium may be taken with food to increase absorption. Consider spacing calcium administration for at least 2 hours before or after consuming foods high in oxalic acid or phytic acid. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

lisdexamfetamine food

Applies to: Vyvanse (lisdexamfetamine)

Using lisdexamfetamine together with alcohol can increase the risk of cardiovascular side effects such as increased heart rate, chest pain, or blood pressure changes. You should avoid or limit the use of alcohol while being treated with lisdexamfetamine. Let your doctor know if you experience severe or frequent headaches, chest pain, and/or a fast or pounding heartbeat. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

famotidine food

Applies to: calcium carbonate / famotidine / magnesium hydroxide

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No duplication warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.