Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- ibuprofen / salicylic acid topical
- isotretinoin
Interactions between your drugs
ISOtretinoin salicylic acid topical
Applies to: isotretinoin, ibuprofen / salicylic acid topical
GENERALLY AVOID: Concomitant use of isotretinoin with topical exfoliative or keratolytic anti-acne agents may increase local skin irritation.
MANAGEMENT: Concurrent use should generally be avoided.
References (2)
- Cerner Multum, Inc. "UK Summary of Product Characteristics."
- Pharmaceutical Society of Australia (2006) APPGuide online. Australian prescription products guide online. http://www.appco.com.au/appguide/default.asp
Drug and food interactions
ISOtretinoin food
Applies to: isotretinoin
GENERALLY AVOID: The combined use of ethanol and isotretinoin may result in a disulfiram-like reaction. The mechanism has not been established.
MANAGEMENT: Alcohol consumption should be avoided during isotretinoin therapy.
References (1)
- (2001) "Product Information. Accutane (isotretinoin)." Roche Laboratories
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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