Drug Interaction Report

Metreleptin may reduce the blood levels of ganaxolone, which may make the medication less effective in some cases. Contact your doctor if your symptoms worsen or your condition changes. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Ganaxolone must be taken with food to ensure adequate absorption of the medication. It is best to avoid or limit the consumption of alcohol, as it can increase drowsiness or other nervous system side effects of ganaxolone. You should also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.