Drug Interaction Report

If you are currently being treated with proguanil, let your doctor know before you receive glucarpidase. There is a possibility that these medications may interfere with each other's effects if they are given too close together. Your doctor may want to separate the dosing times by two to four hours so as to reduce the risk of an interaction, or s/he may want to monitor you more closely to make sure the medications are working as intended. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Food significantly enhances the absorption of atovaquone. You should take each dose of atovaquone at the same time each day with a meal or a milky drink. If you receive enteral nutrition (tube feeding), take atovaquone with your feeding. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication. Talk to your doctor if you have questions or have difficulty taking atovaquone with food.