Drug Interaction Report
1 drug interaction and 4 additional warnings found for the following 2 drugs:
- Extra-Virt Plus DHA (multivitamin, prenatal)
- sodium ferric gluconate complex
Drug interactions
Moderate drug interactions
Moderate:multivitamins, prenatal sodium ferric gluconate complex
Applies to: Extra-Virt Plus DHA (multivitamin, prenatal), sodium ferric gluconate complex
Using multivitamins, prenatal together with sodium ferric gluconate complex may lead to complications from too much iron. In addition, sodium ferric gluconate complex may interfere with the absorption of iron taken by mouth.
You may need to wait at least 5 days after stopping sodium ferric gluconate complex before taking oral iron supplements.
Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition.
It can be intentional, when combining drugs with similar actions adds demonstrated therapeutic benefit — or unintentional, such as when a patient sees multiple prescribers or fills prescriptions at more than one pharmacy, which can lead to adverse effects.
Duplication:Iron preparations
The recommended maximum number of medicines in the 'iron preparations' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'iron preparations' category:
- Extra-Virt Plus DHA (multivitamin, prenatal)
- sodium ferric gluconate complex
Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.
Food/lifestyle interactions
Moderate food/lifestyle interactions
Moderate:Food/Lifestyle multivitamins, prenatal
Applies to: Extra-Virt Plus DHA (multivitamin, prenatal)
Food may reduce the absorption and blood levels of multivitamins, prenatal. In addition, some oral medications can also interfere with multivitamins, prenatal absorption into the bloodstream, which may make the medication less effective in treating your condition. Likewise, multivitamins, prenatal may interfere with the absorption of other orally administered medications.
You should take multivitamins, prenatal on an empty stomach at least one hour before or two hours after a meal.
Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications.
Talk to your doctor or pharmacist if you have questions about how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Disease interactions
2 potential interactionsApplies to: 2 conditions, including Hypotension and Hemodialysis.
Hemodialysis
Moderate:sodium ferric gluconate complex
Sodium ferric gluconate complex has a moderate potential interaction with Hemodialysis.
Sodium ferric gluconate complex injection may cause clinically significant hypotension. Hypotension associated with lightheadedness, malaise, fatigue, weakness or severe pain in the chest, back, flanks, or groin has been reported. These hypotensive reactions may or may not be associated with signs and symptoms of hypersensitivity reactions and usually resolve within one to two hours. Transient hypotension may occur during dialysis and sodium ferric gluconate complex injection may augment hypotension caused by dialysis. Patients with hypotension and patients undergoing dialysis should be monitored for signs and symptoms of hypotension during and following sodium ferric gluconate complex injection administration.
Hypotension
Moderate:sodium ferric gluconate complex
Sodium ferric gluconate complex has a moderate potential interaction with Hypotension.
Sodium ferric gluconate complex injection may cause clinically significant hypotension. Hypotension associated with lightheadedness, malaise, fatigue, weakness or severe pain in the chest, back, flanks, or groin has been reported. These hypotensive reactions may or may not be associated with signs and symptoms of hypersensitivity reactions and usually resolve within one to two hours. Transient hypotension may occur during dialysis and sodium ferric gluconate complex injection may augment hypotension caused by dialysis. Patients with hypotension and patients undergoing dialysis should be monitored for signs and symptoms of hypotension during and following sodium ferric gluconate complex injection administration.
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.