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Drug Interaction Report

5 potential interactions and/or warnings found for the following 2 drugs:

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Interactions between your drugs

Moderate

fosinopril hydroCHLOROthiazide

Applies to: Monopril HCT (fosinopril / hydrochlorothiazide), Monopril HCT (fosinopril / hydrochlorothiazide)

Although fosinopril and hydroCHLOROthiazide are frequently combined together, their effects may be additive on lowering your blood pressure. You may need a dose adjustment or special tests to safely take both medications. Contact your doctor if you have a reduced heart rate, dizziness, fainting, or headaches. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

hydroCHLOROthiazide iodamide

Applies to: Monopril HCT (fosinopril / hydrochlorothiazide), iodamide

Before you undergo any imaging procedure where iodamide may be given by injection, let your doctor know if you are currently being treated with hydroCHLOROthiazide. Injection of iodamide can sometimes cause kidney problems, and the risk may be increased if you are also using hydroCHLOROthiazide. The interaction may be more likely if you have preexisting kidney disease, congestive heart failure, or diabetes; or if you are elderly, dehydrated, or taking other medications that can affect the kidney. Depending on your health situation, your doctor may want you to stop using hydroCHLOROthiazide for a certain length of time before and after the procedure. You may also be asked to increase your fluid intake the day before the procedure, or you may be given intravenous fluids before, during, and after the procedure. Since iodamide contains iodine, also let your doctor know if you have had a previous reaction to iodine or iodine-containing products. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

fosinopril food

Applies to: Monopril HCT (fosinopril / hydrochlorothiazide)

It is recommended that if you are taking fosinopril you should be advised to avoid moderately high or high potassium dietary intake. This can cause high levels of potassium in your blood. Do not use salt substitutes or potassium supplements while taking fosinopril, unless your doctor has told you to.

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Moderate

fosinopril food

Applies to: Monopril HCT (fosinopril / hydrochlorothiazide)

Fosinopril and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

hydroCHLOROthiazide food

Applies to: Monopril HCT (fosinopril / hydrochlorothiazide)

HydroCHLOROthiazide and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No duplication warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.