Povidone K90
Medically reviewed by Drugs.com. Last updated on Nov 18, 2024.
Excipient (pharmacologically inactive substance)
What is it?
Povidone (polyvinylpyrrolidone, PVP) is used in the pharmaceutical industry as a synthetic polymer vehicle for dispersing and suspending drugs. It has multiple uses, including as a binder for tablets and capsules, a film former for ophthalmic solutions, to aid in flavoring liquids and chewable tablets, and as an adhesive for transdermal systems.[1]
Povidone has the molecular formula of (C6H9NO)n and appears as a white to slightly off-white powder. Povidone formulations are widely used in the pharmaceutical industry due to their ability to dissolve in both water and oil solvents. The k number refers to the mean molecular weight of the povidone. Povidones with higher K-values (i.e., k90) are not usually given by injection due to their high molecular weights. The higher molecular weights prevent excretion by the kidneys and lead to accumulation in the body. The best-known example of povidone formulations is povidone-iodine, an important disinfectant.[2]
Some examples of medications containing Povidone K90
- Atenolol 50 mg
- Desvenlafaxine Succinate Extended-Release 50 mg
- Desvenlafaxine Succinate Extended-Release 100 mg
- Diltiazem Hydrochloride 120 mg
- Guaifenesin Extended Release 600 mg
- Ibuprofen 400 mg
- Ibuprofen 600 mg
- Ibuprofen 800 mg
- Metformin Hydrochloride 500 mg
- Metformin Hydrochloride 500 mg
- Metformin Hydrochloride 1000 mg
- Metformin Hydrochloride 500 mg
- Methocarbamol 500 mg
- Methocarbamol 750 mg
- Naproxen 500 mg
- Pantoprazole Sodium Delayed Release 40 mg
- Penicillin V Potassium 500 mg
- Penicillin V Potassium 250 mg
- Valacyclovir Hydrochloride 500 mg
- Valacyclovir Hydrochloride 1 gram
References
- Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 http://drugtopics.modernmedicine.com/drugtopics/Top+News/Overview-of-pharmaceutical-excipients-used-in-tabl/ArticleStandard/Article/detail/561047. Accessed 08/19/2011
- Folttman H, Quadir A. Excipent Update. Polyvinylpyrrolidone (PVP) - one of the mosy widely used excipients in pharmaceuricals: an overview. Drug Delivery Technology. Vol 8;6:22-7. Accessed April 9, 2012. http://www.pharma-ingredients.basf.com/Documents/ENP/Review%20Articles/DDT-June-2008.pdf
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.