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Polacrilin Potassium

Excipient (pharmacologically inactive substance)

Medically reviewed by Drugs.com. Last updated on Jul 24, 2018.

What is it?

Polacrilin potassium is an ion exchange resin used in oral pharmaceutical formulations as a tablet disintegrant. It is a weakly acidic cation exchange resin. Chemically, it is a partial potassium salt of a copolymer of methacrylic acid with divinyl benzene. Physically, ion exchange resins are small plastic beads with a diameter of roughly 0.6 millimeters. [1]

[1] Bele MH, et al. Effect of Polacrilin Potassium as Disintegrant on Bioavailability of Diclofenac Potassium in Tablets : a Technical Note. AAPS PharmSciTech. 2012 Sep; 13(3): 756–59. Accessed February 27, 2015 at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429670/

Further information

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