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Polacrilin Potassium

Excipient (pharmacologically inactive substance)

What is it?

Polacrilin potassium is an ion exchange resin used in oral pharmaceutical formulations as a tablet disintegrant. It is a weakly acidic cation exchange resin. Chemically, it is a partial potassium salt of a copolymer of methacrylic acid with divinyl benzene. Physically, ion exchange resins are small plastic beads with a diameter of roughly 0.6 millimeters. [1]

[1] Bele MH, et al. Effect of Polacrilin Potassium as Disintegrant on Bioavailability of Diclofenac Potassium in Tablets : a Technical Note. AAPS PharmSciTech. 2012 Sep; 13(3): 756–59. Accessed February 27, 2015 at

Further information

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