Hypromellose 2208 (100 MPa.s)
Excipient (pharmacologically inactive substance)
What is it?
Hypromellose, also commonly known as hydroxypropyl methycellulose (HPMC) is a coating agent and film-former used as an inactive ingredient in the pharmaceutical industry.[1] It has also been used as a rate-controlling polymer for sustained-release dose forms.
As a powder, hypromellose is off-white to beige and may be in granules. Hypromellose is considered an inert ingredient. It has a high viscosity and is often used in ophthalmic preparations as artificial tears for dry eyes.[2] In the US, it is available over-the-counter (OTC) in such products as Isopto Tears and Nature’s Tears.
[1] [1]Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 http://drugtopics.modernmedicine.com/drugtopics/Top+News/Overview-of-pharmaceutical-excipients-used-in-tabl/ArticleStandard/Article/detail/561047. Accessed 08/19/2011
[2] Innovate Us. What is Hypromellose? http://www.innovateus.net/health/what-hypromellose. Accessed 08/19/2011
Top Medications with this excipient
- Acetadryl acetaminophen 500 mg / diphenhydramine hydrochloride 25 mg (Physicians Science & Nature, Inc.)
- Alprazolam Extended Release 1 mg (Aurobindo Pharma Limited)
- Citalopram Hydrochloride 20 mg (Epic Pharma, LLC)
- Clarithromycin 500 mg (Roxane Laboratories, Inc.)
- Escitalopram Oxalate 10 mg (base) (West-Ward Pharmaceutical Company)
- Escitalopram Oxalate 20 mg (base) (West-Ward Pharmaceutical Company)
- Montelukast Sodium 10 mg (base) (Qualitest Pharmaceuticals)
- Naltrexone Hydrochloride 50 mg (Sandoz Pharmaceuticals Inc.)
- Omeprazole 20 mg (Sandoz Pharmaceuticals Inc.)
- Omeprazole 10 mg (Sandoz Pharmaceuticals Inc.)
- Omeprazole Delayed Release 40 mg (Sandoz Pharmaceuticals Inc.)
- Oxybutynin Chloride Extended-Release 10 mg (Kremers Urban)
- Oxybutynin Chloride Extended-Release 5 mg (Kremers Urban)
- Oxybutynin Chloride Extended-Release 15 mg (Kremers Urban)
- Pantoprazole Sodium Delayed Release 40 mg (ESI Lederle Generics)
- Pantoprazole Sodium Delayed Release 20 mg (Wyeth Pharmaceuticals)
- Tacrolimus 1 mg (Sandoz Pharmaceuticals Inc.)
- Tacrolimus 0.5 mg (Sandoz Pharmaceuticals Inc.)
- Theophylline Extended-Release 300 mg (Pliva Inc.)
- Theophylline Extended-Release 200 mg (Pliva Inc.)
