Ethylcellulose (20 MPa.s)
Excipient (pharmacologically inactive substance)
What is it?
Ethylcellulose is a free-flowing, white to light tan powder used in the pharmaceutical and food manufacturing industries. It is prepared from wood pulp or cotton by treatment with alkali and ethylation of the alkali cellulose with ethyl chloride. Ethylcellulose is used in pharmaceutical industry as a coating agent, flavoring fixative, tablet binder and filler, and as a viscosity-increasing agent. Ethyl cellulose is also used in the food industry as an emulsifier.[1][2]
There is very limited data detailing possible side effects of ethylcellulose; however it is included in the FDA generally regarded as safe (GRAS) Database of Substances (SCOGS) Reviews.[3]
[1] [1]Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 http://drugtopics.modernmedicine.com/drugtopics/Top+News/Overview-of-pharmaceutical-excipients-used-in-tabl/ArticleStandard/Article/detail/561047. Accessed 08/19/2011
[2] Food and Agriculture Organization of the United States. Prepared at the 26th JECFA (1982), published in FNP 25 ( 1982) and FNP. 52 (1992). Accessed March 31, 2012. Ethylcellulose. http://www.fao.org/ag/agn/jecfa-additives/specs/Monograph1/Additive-178.pdf
[3] FDA’s SCOGS database; Ethylcellulose; SCOGS-Report Number: 25; http://www.accessdata.fda.gov/scripts/fcn/fcnDetailNavigation.cfm?rpt=scogsListing&id=365 Accessed March 31, http://www.accessdata.fda.gov/scripts/fcn/fcnDetailNavigation.cfm?rpt=scogsListing&id=119
Top Medications with this excipient
- Carbamazepine Extended Release 300 mg (Nostrum Laboratories, Inc.)
- Carbamazepine Extended Release 100 mg (Nostrum Laboratories, Inc.)
- Carbamazepine Extended Release 200 mg (Nostrum Laboratories, Inc.)
- Dextroamphetamine Sulfate Extended Release 5 mg (Mallinckrodt Pharmaceuticals)
- Diltiazem Hydrochloride Extended-Release (CD) 240 mg (Sun Pharmaceutical Industries Ltd)
- Diltiazem Hydrochloride Extended-Release (CD) 300 mg (Sun Pharmaceutical Industries Inc.)
- Diltiazem Hydrochloride Extended-Release (CD) 360 mg (Sun Pharmaceutical Industries Inc.)
- Diltiazem Hydrochloride Extended-Release (CD) 180 mg (Sun Pharmaceutical Industries Inc.)
- Diltiazem Hydrochloride Extended-Release (CD) 120 mg (Sun Pharmaceutical Industries Ltd)
- Isentress (Chewable) 100 mg (Merck Sharp & Dohme Corp.)
- Isentress (Chewable) 25 mg (Merck Sharp & Dohme Corp.)
- Klor-Con M10 10 mEq (Upsher-Smith Laboratories, Inc)
- Klor-Con M15 15 mEq (Upsher-Smith Laboratories, Inc)
- Klor-Con M20 20 mEq (Upsher-Smith Laboratories, Inc)
- Venlafaxine Hydrochloride Extended Release 37.5 mg (Aurobindo Pharma Limited)
- Venlafaxine Hydrochloride Extended Release 75 mg (Aurobindo Pharma Limited)
- Venlafaxine Hydrochloride Extended Release 150 mg (Aurobindo Pharma Limited)
- Venlafaxine Hydrochloride Extended Release 150 mg (Aurobindo Pharma Limited)
