Ethylcellulose (100 MPa.s)
Excipient (pharmacologically inactive substance)
What is it?
Ethylcellulose is a free-flowing, white to light tan powder used in the pharmaceutical and food manufacturing industries. It is prepared from wood pulp or cotton by treatment with alkali and ethylation of the alkali cellulose with ethyl chloride. Ethylcellulose is used in pharmaceutical industry as a coating agent, flavoring fixative, tablet binder and filler, and as a viscosity-increasing agent. Ethyl cellulose is also used in the food industry as an emulsifier.[1] [2]
There is very limited data detailing possible side effects of ethylcellulose; however it is included in the FDA generally regarded as safe (GRAS) Database of Substances (SCOGS) Reviews.[3]
[1] Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 http://drugtopics.modernmedicine.com/drugtopics/Top+News/Overview-of-pharmaceutical-excipients-used-in-tabl/ArticleStandard/Article/detail/561047. Accessed 08/19/2011
[2] Food and Agriculture Organization of the United States. Prepared at the 26th JECFA (1982), published in FNP 25 ( 1982) and FNP. 52 (1992). Accessed March 31, 2012. Ethylcellulose. http://www.fao.org/ag/agn/jecfa-additives/specs/Monograph1/Additive-178.pdf
[3] FDA’s SCOGS database; Ethylcellulose; SCOGS-Report Number: 25; http://www.accessdata.fda.gov/scripts/fcn/fcnDetailNavigation.cfm?rpt=scogsListing&id=365 Accessed March 31, http://www.accessdata.fda.gov/scripts/fcn/fcnDetailNavigation.cfm?rpt=scogsListing&id=119
Top Medications with this excipient
- Aplenzin 174 mg
- Aplenzin 522 mg
- Carbamazepine 200 mg
- Clarinex-D 24 Hour 5 mg / 240 mg
- Copegus 200 mg
- Dextroamphetamine Sulfate Extended Release 5 mg
- Dextroamphetamine Sulfate Extended Release 15 mg
- Dextroamphetamine Sulfate Extended Release 10 mg
- Effexor XR 75 mg
- Effexor XR 37.5 mg
- Effexor XR 150 mg
- Epitol 200 mg
- Lamictal ODT 25 mg
- Lamictal ODT 100 mg
- Lamictal ODT 200 mg
- Micro-K 8 mEq
- Namenda XR 14 mg
- Namenda XR 21 mg
- Prenatal Plus Prenatal Vit 27 mg Fe Fumarate 1 mg
- Venlafaxine Hydrochloride Extended-Release 37.5 mg
