Calcium Stearate
Excipient (pharmacologically inactive substance)
What is it?
Calcium stearate (C36H70CaO4) is a mixture of calcium oxide with solid fatty acids such as stearic and palmitic acids. It is used as pharmaceutical excipient in manufacturing and used for tablet and capsule lubrication. It has good anti-adherent and lubricant properties but poor glidant properties. Calcium stearate is also used in cosmetics and food products.[1]
Calcium stearate is used in oral drug formulations and is reported as nontoxic and nonirritant. It is listed on the FDA Generally Regarded as Safe database.[1][2]
[1] Medicines Complete. Pharmaceutical Excipients. Monographs. Copovidone. Accessed April 8, 2012. http://www.medicinescomplete.com/mc/excipients/current/1001936849.htm#_1002015028
[2] FDA’s SCOGS database; calcium stearate; SCOGS-Report Number: 59; Accessed April 9, 2012. http://www.accessdata.fda.gov/scripts/fcn/fcnDetailNavigation.cfm?rpt=scogsListing&id=66
Top Medications with this excipient
- Diazepam 5 mg (Qualitest Pharmaceuticals Inc.)
- Diazepam 10 mg (Qualitest Pharmaceuticals Inc.)
- Diazepam 2 mg (Qualitest Pharmaceuticals Inc.)
- Gabapentin 600 mg (Actavis)
- Gabapentin 800 mg (Actavis)
- Gemfibrozil 600 mg (Major Pharmaceuticals Inc.)
- Gemfibrozil 600 mg (Teva Pharmaceuticals USA)
- Hydrochlorothiazide 12.5 mg (Actavis)
- Lithium Carbonate 300 mg (Roxane Laboratories, Inc.)
- Lithium Carbonate Extended Release 300 mg (Roxane Laboratories, Inc.)
- Nitrostat 0.4 mg (Pfizer U.S. Pharmaceuticals Group)
- Orphenadrine Citrate Extended Release 100 mg (Sandoz Pharmaceuticals Inc.)
- Oxybutynin Chloride 5 mg (Pliva Inc.)
- Oxybutynin Chloride 5 mg (Upsher-Smith Laboratories, Inc)
- Pantoprazole Sodium Delayed Release 40 mg (ESI Lederle Generics)
- Pantoprazole Sodium Delayed-Release 40 mg (Teva Pharmaceuticals USA)
- Protonix 40 mg (Wyeth)
- Valium 10 mg (Roche Laboratories)
- Valium 5 mg (Roche Laboratories)
- Valium 2 mg (Roche Laboratories)
