Calcium Stearate
Excipient (pharmacologically inactive substance)
What is it?
Calcium stearate (C36H70CaO4) is a mixture of calcium oxide with solid fatty acids such as stearic and palmitic acids. It is used as pharmaceutical excipient in manufacturing and used for tablet and capsule lubrication. It has good anti-adherent and lubricant properties but poor glidant properties. Calcium stearate is also used in cosmetics and food products.[1]
Calcium stearate is used in oral drug formulations and is reported as nontoxic and nonirritant. It is listed on the FDA Generally Regarded as Safe database.[1][2]
[1] Medicines Complete. Pharmaceutical Excipients. Monographs. Copovidone. Accessed April 8, 2012. http://www.medicinescomplete.com/mc/excipients/current/1001936849.htm#_1002015028
[2] FDA’s SCOGS database; calcium stearate; SCOGS-Report Number: 59; Accessed April 9, 2012. http://www.accessdata.fda.gov/scripts/fcn/fcnDetailNavigation.cfm?rpt=scogsListing&id=66
Top Medications with this excipient
- Cefuroxime Axetil 250 mg (Ascend Laboratories LLC.)
- Diazepam 5 mg (Qualitest Pharmaceuticals Inc.)
- Diazepam 10 mg (Qualitest Pharmaceuticals Inc.)
- Disopyramide Phosphate 150 mg (Ethex Corporation)
- Gabapentin 600 mg (Actavis)
- Gabapentin 800 mg (Actavis)
- Hexalen 50 mg (MGI Pharma Inc)
- Irbesartan 75 mg (Camber Pharmaceuticals, Inc.)
- Irbesartan 150 mg (Camber Pharmaceuticals, Inc.)
- Irbesartan 300 mg (Camber Pharmaceuticals, Inc.)
- Orphenadrine Citrate Extended Release 100 mg (Sandoz Pharmaceuticals Inc.)
- Pantoprazole Sodium 40 mg (Torrent Pharmaceuticals)
- Pantoprazole Sodium Delayed Release 40 mg (ESI Lederle Generics)
- Pantoprazole Sodium Delayed-Release 40 mg (Aurobindo Pharma Limited)
- Pantoprazole Sodium Delayed-Release 40 mg (Teva Pharmaceuticals USA)
- Potassium Chloride Extended-Release 10 mEq (750 mg) (Ethex Corporation)
- Tamsulosin Hydrochloride 0.4 mg (Aurobindo Pharma Limited)
- Tamsulosin Hydrochloride 0.4 mg (Mylan Pharmaceuticals Inc.)
- Valium 10 mg (Roche Laboratories)
- Valium 5 mg (Roche Laboratories)
