Vorasidenib and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with vorasidenib.
Vorasidenib Food/Lifestyle
Moderate Food Interaction
GENERALLY AVOID: Due to induction of CYP450 1A2, the isoenzyme primarily responsible for the metabolic clearance of vorasidenib, smoking tobacco during treatment with vorasidenib may decrease its plasma concentrations and anti-tumor effect. Clinical and pharmacokinetic data are currently lacking.
MANAGEMENT: Patient should be advised to avoid smoking tobacco during treatment with vorasidenib because it may reduce efficacy of the therapy.
References (1)
- (2024) "Product Information. Voranigo (vorasidenib)." Servier Pharmaceuticals LLC
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Vorasidenib drug interactions
There are 440 drug interactions with vorasidenib.
Vorasidenib disease interactions
There are 3 disease interactions with vorasidenib which include:
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- Drug class: miscellaneous antineoplastics
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
