Olpruva and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Olpruva (sodium phenylbutyrate).
Sodium Phenylbutyrate Food
Moderate Food Interaction
Food may affect the absorption of sodium phenylbutyrate. A high-fat, high-calorie meal (approximately 800 to 1000 calories; 500 to 600 calories from fat, 250 calories from carbohydrate, 150 calories from protein) has been shown to reduce the absorption of sodium phenylbutyrate, although it is unknown what impact this may have on the overall effectiveness of the medication. The manufacturer recommends taking sodium phenylbutyrate before a meal or snack. This is especially important if you weigh less than 70 kg (approximately 154 pounds). Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.
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Olpruva drug interactions
There are 34 drug interactions with Olpruva (sodium phenylbutyrate).
Olpruva disease interactions
There are 3 disease interactions with Olpruva (sodium phenylbutyrate) which include:
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Sodium phenylbutyrate
Sodium phenylbutyrate systemic is used for urea cycle disorders
Glycerol phenylbutyrate
Glycerol phenylbutyrate systemic is used for urea cycle disorders
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.