Rezlidhia and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Rezlidhia (olutasidenib).
Olutasidenib Food/Lifestyle
Moderate Food Interaction
ADJUST DOSING INTERVAL: Coadministration with a high-fat meal may increase the plasma concentrations of olutasidenib. According to the product labeling, administration of a single 150 mg dose with a high-fat meal (approximately 800 to 1000 calories, with approximately 50% of those calories from fat) increased olutasidenib peak plasma concentration (Cmax) and systemic exposure (AUC) by 191% and 83%, respectively, in healthy subjects.
MANAGEMENT: Olutasidenib should be administered at about the same time each day, on an empty stomach at least 1 hour before or 2 hours after a meal.
References (1)
- (2022) "Product Information. Rezlidhia (olutasidenib)." Rigel Pharmaceuticals
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Rezlidhia drug interactions
There are 488 drug interactions with Rezlidhia (olutasidenib).
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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