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Heartworm Prevention in Your Pet

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Heartworm is a difficult-to-treat and potentially fatal disease in dogs and cats, but it can be prevented with drugs approved by the Food and Drug Administration (FDA). Owners have a variety of products to choose from to help keep their pets heartworm-free.

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Heartworm Disease

A dog or cat can get heartworm disease through a mosquito bite. If the mosquito is carrying the heartworm larvae (infective stage) when it bites a pet, the disease is likely to be transmitted to the pet. The larvae enter the bite wound and move through the pet's body. The adult worms live in the heart, lungs, and nearby blood vessels, where they can grow up to 12 inches long.

Dogs, cats, and some other mammals can get heartworms only if bitten by an infected mosquito; the disease is not contagious from one animal to another. Heartworms in humans are very rare.

Most dogs and cats with heartworm infection do not show any symptoms until the disease becomes severe. At that stage, symptoms may include

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Prevention Vs. Treatment

"Prevention is much easier than treatment," says Martine Hartogensis, D.V.M., a veterinarian in FDA's Center for Veterinary Medicine (CVM), because most heartworm preventive products are given to pets only once a month.

"Treatment for dogs can have serious side effects, requires multiple injections, and may involve blood work and x-rays before treatment,” says Hartogensis. "Dogs need to be closely monitored during treatment and for up to 24 hours after treatment. Also, the drug used to kill adult heartworms in dogs is currently only available in limited quantities.”

Following treatment for heartworm disease, dogs should have restricted exercise for up to six weeks, adds Hartogensis, because active dogs are at risk for death from a clot in the lungs.

There is no heartworm treatment approved for cats; medications may help manage the symptoms.

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Types of Heartworm Preventives

A variety of products are available by prescription only:

A few heartworm preventives are combined with other ingredients to kill fleas and some types of ticks and intestinal parasites.

Because pets that have heartworms may not show symptoms right away, your veterinarian may test your pet before prescribing heartworm preventive, and then yearly, to make sure the pet is not infected. Dogs are tested for heartworm using a simple blood test. Testing in cats, however, is more difficult than, and not as accurate as, testing in dogs.

"Talk to your veterinarian about testing and the best heartworm preventive program for you and your pet," says Hartogensis. "Your veterinarian's recommendation may depend on where you live and whether your pet spends time inside or outside." Heartworms have been found in all 50 states, according to the American Heartworm Society, but they are more commonly found in some areas of the country than others.

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Injectable Heartworm Preventive

ProHeart 6 (moxidectin) Sustained Release Injectable for Dogs is the only six-month injectable heartworm preventive approved in the United States. First approved in 2001, ProHeart 6 was voluntarily recalled by the original manufacturer, Fort Dodge Animal Health, in 2004 based on FDA's concerns regarding reports of serious side effects, including death. In June 2008, FDA concurred with Fort Dodge's decision to reintroduce ProHeart 6 to the U.S. market under a special program to manage the risks and restrict distribution. After the recall, Fort Dodge