Drug Interactions between Velphoro and Vitamin D3
This report displays the potential drug interactions for the following 2 drugs:
- Velphoro (sucroferric oxyhydroxide)
- Vitamin D3 (cholecalciferol)
Interactions between your drugs
cholecalciferol sucroferric oxyhydroxide
Applies to: Vitamin D3 (cholecalciferol) and Velphoro (sucroferric oxyhydroxide)
GENERALLY AVOID: Coadministration with sucroferric oxyhydroxide may reduce the oral bioavailability of vitamin D analogs. The proposed mechanism involves nonspecific adsorption to the ferric ion component of sucroferric oxyhydroxide, resulting in an insoluble complex that is poorly absorbed from the gastrointestinal tract. According to the product labeling for sucroferric oxyhydroxide, an in vitro interaction with paricalcitol was observed when studied in aqueous solutions that mimic the physico-chemical conditions of the gastrointestinal tract.
MANAGEMENT: Oral formulations of vitamin D analogs should not be prescribed with sucroferric oxyhydroxide.
References
- (2014) "Product Information. Velphoro (sucroferric oxyhydroxide)." Fresenius Medical Care North America
Drug and food interactions
No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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